© 2023 International Health Terminology Standards Development Organisation. All rights reserved. SNOMED CT® was originally created by the College of American Pathologists.
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Page At A Glance
Table Of Contents
SNOMED CT terminology provides a common language that enables a consistent way of indexing, storing, retrieving, and aggregating clinical data across specialties and sites of care.
SNOMED International maintains the SNOMED CT technical design, the content architecture, the SNOMED CT content (includes the concepts table, the descriptions table, the relationships table, a history table, and ICD mappings), and related technical documentation.
This document provides a summarized description of the content changes included in the May 2022 release of SNOMED Clinical Terms® (SCT) International Release.
It also includes technical notes detailing the known content or technical issues where the root cause is understood, the fix has been discussed and agreed to, but has yet to be implemented.
The SNOMED International Release Notes are available alongside the May 2022 International release.
This document is written for the purpose described above and is not intended to provide details of the technical specifications for SNOMED CT or encompass every change made during the release.
The audience includes National Release Centers, WHO-FIC release centers, vendors of electronic health records, terminology developers and managers who wish to have an understanding of changes that have been incorporated into the May 2022 International release.
Please note, you may have to register for a Confluence user account in order to access the links included in these release notes.
1.5. Changes to the International Edition Release Schedule
SNOMED International have transitioned to a more frequent (monthly) delivery schedule for the International Edition of SNOMED CT. The move towards more frequent releases of SNOMED CT will realise several benefits, including:
- The potential to be able to get content changes into the terminology in a shorter time frame.
- The fostering of better interoperability, as a result of entities being able to consume release content that is more aligned with other organizations.
- The prevention of circular dependencies that occur in longer projects, due to the move towards smaller, more manageable authoring projects.
- More automated validation services, as a result of the inherent removal of the Alpha/Beta stages in the Release cycle.
Whilst most users will continue unaffected (as they can simply continue to download the releases every 6 months as always), this transition necessarily involved a few changes to process/packages:
- The Member Release period is no longer be required within the new rapid monthly release schedules. If you would like to continue assisting in the validation efforts of SNOMED CT there are other ways in which you can help - please contact email@example.com to find out more.
- Delta files have been removed from the release package - a Delta Generation service will be provided for those who need it. The Delta Generation Tool allows users to create their own Delta between two fixed release dates - you can find it here:
- The ICD-0/ICD-10 Maps will continue to be published in each Monthly International Edition release package (in line with that month's content) for the foreseeable future, unless we experience issues with the new process in Production, and they need to be removed at a later date.
NOTE: SNOMED International worked closely with Members over the past couple of years to better understand the impact of the proposed model, and have incorporated feedback into the new processes. This was designed to prevent any adverse impact to users, however if you have any further questions or concerns please see the FAQ's here, or contact us on firstname.lastname@example.org.
2. Content Development Activity
Continuous quality improvement and enhancement of existing content is an ongoing process undertaken by SNOMED International in preparation for every release. The May 2022 International Release has seen a continuation of the work driven by contributions from: Kaiser Permanente i.e. Convergent Medical Terminology (CMT), Global Medical Device Nomenclature Agency (GMDNA), Orphanet and other domain specific collaborations as well as requests received via the Content Request System (CRS).
Additionally quality improvement activities are advanced via project driven initiatives summarized below. Additional work items impacting every release are updates to the SNOMED CT derived maps such as ICD-10 and ICD-O; details are included in these release notes.
Content relating to COVID-19 can be viewed here SNOMED CT COVID-19 Related Content
Any concepts in scope for the SNOMED CT to ICD-10 mapping have been mapped and adhere to the World Health Organization current guidelines.
2.3. Inactivation Changes
Please see new editorial guidance for changes to inactivation values here
2.4. Quality Initiative
The Quality Initiative (QI) project is the implementation of the Quality Strategy. After a successful pilot project for the July 2018 release the next stage has been implemented for subsequent releases including May 2022.
Quality improvement tasks were deployed to improve internal structural consistency and ensure compliance with editorial policy related to the stated modeling of content. Additionally, correction or addition of defining relationships was carried out to accurately reflect current clinical knowledge and ensure the semantic reliability of descriptions associated with a concept.
Information about the project can be found here
2.5. Body Structure
2.5.1. SEP and Laterality Anatomy Reference Sets
Updated and validated release file for the lateralizable body structure reference set.
Updated and validated release files for the SEP refsets.
2.6. Clinical Finding
NOTE: 'Co-occurrent and due to' pattern:
During the implementation of the new Description Logic features, a conflict was uncovered between the modeling of 'Co-occurrent and due to' and General Concept Inclusions (GCIs). This has resulted in the need to reconsider the modeling of "Co-occurrent and due to' and update the Editorial Guide for this area.
The Editorial Guide and all concepts that are currently modeled as 'Co-occurrent and due to' will be updated over future release cycles.
2.6.1. Inactivation of Legal/Illegal Abortion Concepts
As approved by the SNOMED Editorial Advisory Group, concepts referring to "legal" and "illegal" termination of pregnancy (abortion) have been inactivated from the international release with reason non-conformance to editorial policy and replaced by concepts agnostic as to the legality of the procedure.
2.6.2. Remodeling of 277643003|High grade T-cell lymphoma (disorder)| Subtypes
Based on user feedback, and to align with the ICD-O-3.2 classification and other research, a new concept 1222550009 |Enteropathy-associated T-cell lymphoma (morphologic abnormality)| that is a subtype of 103686008 |Intestinal T-cell lymphoma (morphologic abnormality)| has been created and used to Sufficiently Define existing concept 277654008 |Enteropathy-associated T-cell lymphoma (disorder)|.
ICD-O-3.2 confirms that existing synonyms Peripheral T-cell lymphoma, pleomorphic medium and large cell and Peripheral T-cell lymphoma, pleomorphic small cell are correctly placed as synonyms of 1163404000 |Peripheral T-cell lymphoma (morphologic abnormality)| therefore 277653002 |Peripheral T-cell lymphoma - pleomorphic medium and large cell (disorder)| and 277651000 |Peripheral T-cell lymphoma - pleomorphic small cell (disorder)| have been inactivated as duplicate and the descriptions added to 109977009 |Peripheral T-cell lymphoma (disorder)|.
277643003 |High grade T-cell lymphoma (disorder)| is now defined with 314927000 |High grade T-cell lymphoma morphology (morphologic abnormality)|.
2.6.3. Remodeling of 68225006|Alopecia areata (disorder)| and Subtypes
370135005|Pathological process (attribute)| and 263680009|Autoimmune process (qualifier value)| has been added to 68225006 |Alopecia areata (disorder)| and subtypes, these concepts now classify as a subtype of 85828009|Autoimmune disease (disorder)|.
2.6.4. Remodeling of Subtypes of 111197009 |Lichen myxedematosus (disorder)|
A new concept has been added 1222586005 |Localized lichen myxedematosus (disorder)|
A combined morphology for lichenification and mucinosis has been added 1222603008 |Lichen mucinosis (morphologic abnormality)| and this area of content in the disorder hierarchy has been remodeled.
2.6.5. 47429007|Associated with (attribute)| - Self-Grouped
Concepts that had grouped 47429007|Associated with (attribute)| with other attribute-value pairs were remodeled to have the 47429007|Associated with (attribute)| self-grouped to align with editorial policy.
2.6.6. Inactivation of 95217000 |Pseudophakia (disorder)| and Subtypes
95217000 |Pseudophakia (disorder)| and descendants have been inactivated as respective duplicates exist in the form of 309523001 |Artificial lens present (finding)|.
NOTE: Disorder X without Disorder Y
The vast majority of existing X without Y concepts originated from ICD-9 with the specific meaning of "X disorder without mention of Y disorder". As the phraseology indicates a lack of data about disorder Y as opposed to a specific exclusion, this type of concept has not been included in ICD-10, nor proposed for ICD-11, except in the case of "Traumatic brain injury without open intracranial wound".
Addition of new X without Y concepts may only be made under the following conditions:
For the most part, existing X without Y concepts will be inactivated as AMBIGUOUS with a historical MAY BE relationship to "X disorder". Exceptions to inactivation will be made on a case-by-case basis.
2.7.1. New Concepts for Replacement of Joint/Revision of Joint
Five new concepts have been created in the procedure hierarchy for Revision of total replacement of hip joint and Revision of total replacement of knee joint using various prosthetic devices and grafts including cone, stem, mesh, cup-cage.
Seven new concepts have been created in the procedure hierarchy for Total replacement of hip joint and Total replacement of knee joint using various prosthetic devices and grafts including cone, stem, mesh, cup-cage.
2.7.2. Inactivation of Endoscopy Procedures Stating Therapeutic or Diagnostic Intent
Following consultation with the community of practice, work has been completed in the May 2022 release to inactivate endoscopy content stating intent as diagnostic or therapeutic. The inactivation reason is Non-conformance to editorial policy and REPLACED BY an intent agnostic concept.
2.7.3. Nursing Procedure Content
13 new nursing procedure concepts have been added.
2.8. Qualifier Value
NOTE: Planned Inactivation of 260299005 |Number (qualifier value)| and Descendants
Following the deployment of the concrete domain functionality in SNOMED CT, concepts in the 260299005 |Number (qualifier value)| hierarchy are no longer necessary and plans have been made for their inactivation. To provide adequate time for any national extension or implementation affected by this change, concepts in the 260299005 |Number (qualifier value)| hierarchy will be inactivated in the January 2023 International Release.
Concepts will be inactivated with reason “Non-conformance to editorial policy” and no historical relationship or replacement concept will be provided.
118586006 |Ratio (property) (qualifier value)| and descendants have been relocated to 118598001 |Property (qualifier value)| hierarchy.
272070003 |Ordinal number (qualifier value)| and descendants have been relocated to 362981000 |Qualifier value (qualifier value)| hierarchy.
A briefing note will also be distributed to selected Advisory and Project Groups.
Please contact email@example.com with any inquiries.
2.9.1. New Concepts
28 new protein substance concepts added.
15 existing protein substance concepts modified to align with authoritative source.
This work was undertaken in support of the Cancer Synoptic Reporting Project Group to enable defining immunohistochemistry neoplastic observables.
2.10. Pharmaceutical/Biological Product
2.10.1. New Dose Form Grouper Concepts
New pharmaceutical dose form grouper concepts, and corresponding clinical drug concepts, specifying “infusion and/or injection” have been added to the Pharmaceutical dose form and Medicinal product hierarchies, respectively.
2.11. Physical Object
2.12. Collaboration/Harmonization Agreements
2.12.1. Convergent Medical Terminology (CMT)
82 concepts have been added for the May 2022 release from the domains musculoskeletal and ophthalmology.
Working in collaboration with Orphanet (http://www.orpha.net/consor/cgi-bin/index.php), creation of new concepts for the original set of prioritized rare diseases has been completed. All of the concepts added for the Orphanet project have been mapped to ICD-10.
The Production release of the SNOMED CT to Orphanet Simple Map was published in October 2021. Work is now underway to add further content to the SNOMED CT to Orphanet Simple Map for future releases starting with the next Production release in October 2022.
2.12.3. ICD-11 Update
The May 2022 release has seen continued addition of content for this project.
2.12.4. Cancer Synoptic Reporting
Cancer synoptic reports are used by many member countries to record pathology examination of cancer specimens including the College of American Pathologists (US and Canada), Royal College of Pathology (UK), Royal College of Pathology Australasia (Australia, New Zealand), PALGA (The Netherlands), Swedish Society of Pathology, and others.
For more information about this project, please see Cancer Synoptic Reporting Clinical Project Group
2.13. Internal Quality Improvement
2.13.1. Machine Readable Concept Model (MRCM) Changes
Details for forthcoming changes can be reviewed here
NOTE: Advance Notice of Cardinality Changes Scheduled for July 2022 Release
All historical content issues where two or more finding sites were included in a single role group have been resolved in the International release as part of the QI project.
There are two MRCM rules for finding site to accommodate the historical content. One MRCM is applicable to all content, it allows more than one finding site in a role group. The other MRCM is only applicable for 'All new precoordinated SNOMED CT content'.
The existing MRCM rules will be updated to only allow at most one finding site in a role group from the July 2022 release.
This early notice is intended to provide additional time for content updates in national extensions.
Please contact firstname.lastname@example.org with any inquiries.
2.14. SNOMED CT derived products
2.14.1. ICD-10 map
The SNOMED CT to the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (© World Health Organization 1994) 2016 Version map (SNOMED CT to ICD-10 Map) is included in the SNOMED CT International release as a Baseline. The SNOMED CT to ICD-10 Map was created to support the epidemiological, statistical and administrative reporting needs of SNOMED International member countries and WHO Collaborating Centers.
The SNOMED CT to ICD-10 Map is released in Release Format 2 (RF2) only. It is located in the file der2_iisssccRefset_ExtendedMapFull_INT_20200731.txt, which is in the Map folder under Refset, in each of the three RF2 Release Type folders.
The SNOMED CT to ICD-10 Map is released as Refset 447562003 |ICD-10 complex map reference set (foundation metadata concept)|.
2.14.2. Content development activity summary
The map is a directed set of relationships from SNOMED CT source concepts to ICD-10 target classification codes. The SNOMED CT source domains for the MAP are limited to subtypes of 404684003 |clinical finding|, 272379006 |event| and 243796009 |situation with explicit context|. The target classification codes are ICD-10 2016 release.
Mapped content for May 2022
The map provided for the May 2022 release has been updated, and now represents a complete map from SNOMED CT International release to ICD-10 2016 version.
311 newly authored concepts have been added and mapped.
The SNOMED to ICD-O (morphology) map has 1 additional concept added as a result of the ICD-O 3.2 review or added due to CRS requests.
We would welcome feedback on any issues that users of the map may detect when using the map. Issues should be submitted via email@example.com
2.14.3. Technical Guide Exemplars
The Technical Guide Exemplars document has now been moved from the International Edition release package to a Confluence page. This page can be found as part of the ICD-10 Mapping Technical Guide (see Appendix B), which is hosted here: http://snomed.org/icd10map
2.14.4. SNOMED CT to OWL conversion and classification
The repository containing the toolkit enabling simple SNOMED CT to OWL conversion and classification can be found here, including documentation on its use: https://github.com/IHTSDO/snomed-owl-toolkit
Please contact SNOMED International at firstname.lastname@example.org if you would like to provide any feedback on ways to extend and improve the new toolkit.
3. Technical notes
3.1. Known Issues
Known Issues are content or technical issues where the root cause is understood, and the resolution has been discussed and agreed but has yet to be implemented. This can be due to a number of reasons, from lack of time within the new monthly editing cycles, to the risk of impact to the stability of SNOMED CT if the fix were to be deployed at that stage in the Product lifecycle.
For the current SNOMED CT International edition, the following Known Issues were identified, and agreed to be resolved in future editing cycles:
3.2. Resolved Issues
Resolved issues are Known Issues which were not fixed as part of the previous release lifecycle, but which have now been resolved in the latest release. They can also be issues found during testing of the current release, which were resolved before the final deployment of the Production release. Finally they can be issues which were reported or found during the testing phase, but which have been closed without any action taken.
The Resolved Issues for the current SNOMED CT International edition can be found here:
3.3. Technical updates
3.3.1. RF2 package format
For future reference, the RF2 package convention dictates that it contains all relevant files, regardless of whether or not there is content to be included in each particular release. Therefore, the package contains a mixture of files which contain both header rows and content data, and also files that are intentionally left blank (including only a header record). The reason that these files are not removed from the package is to draw a clear distinction between files that:
have been deprecated (and therefore removed from the package completely), due to the content no longer being relevant to RF2 in this or future releases, and
happen to contain no data in this particular release (and are therefore included in the package but left blank, with only a header record), but are still relevant to RF2, and could therefore potentially contain data in future releases.
This allows users to easily distinguish between files that have purposefully been removed or not, as otherwise if files in option 2 above were left out of the package it could be interpreted as an error, rather than an intentional lack of content in that release.
Configuration file in the RF2 package, containing Release Metadata
A new file has been included since the July 2020 International Edition, containing metadata about the Release package itself. This has been created in conjunction with feedback from the community, and as such initially contains the following fields:
The file is in .JSON format, to ensure that it is both machine-readable and human-readable, and is named "release_package_information.json".
The metadata will be extended and refined going forward, in order to ensure that it contains the most useful information possible. If you have any ideas about any other useful information to include, please send them to email@example.com, along with a business case explaining how the information would benefit stakeholders. Please be aware that this use case will then be assessed by SNOMED International, and the new metadata will only be included in the configuration file if the business case is strong enough.
3.3.2. New Association References
In order to support the Content changes above in section 2.3. Concept Inactivation Changes, the following Association Reference set members have been added to the International Edition from the April 2022 release onwards:
- 1186921001|POSSIBLY REPLACED BY association reference set
- 1186924009|PARTIALLY EQUIVALENT TO association reference set
3.3.3. Early visibility of impending changes in the upcoming 2022 Monthly International Edition releases
Please see the following page for details of all upcoming changes planned for 2022:
3.3.4. Document links
All links provide information that is correct and current at the time of this Release. Updated versions may be available at a later date, but if so these will need to be requested from the relevant SNOMED International teams.
NOTE: To access any of the links in the pdf document, please visit the Release Notes @
Draft Amendment History
First draft for review and comment
|Maria Braithwaite||Initial content updates|
|Maria Braithwaite||Final Content changes|
|Final Production changes|