Laboratory testing for COVID-19 and the associated SARS-CoV-2 virus includes methods that detect the presence of the virus and antibodies produced in response to infection, in specimen samples taken from potentially infected individuals. Test and investigation data which can be recorded using SNOEMD CT includes:
These data elements are described below, with example SNOMED CT subsets for each.
2.4.1 Specimen
Specimens are samples of substances taken from an individual for testing - for example 258500001 | Nasopharyngeal swab (specimen)| or 119339001 | Stool specimen (specimen)| . The following specimens may be relevant to COVID-19 testing in one or more countries affected by the virus.
| CV19-INV-Specimen | |||
|---|---|---|---|
| Concept id | Fully Specified Name | en-US Preferred Term | Effective Time |
| 258607008 | Bronchoalveolar lavage fluid sample (specimen) | Bronchoalveolar lavage fluid sample | 20080731 |
| 258500001 | Nasopharyngeal swab (specimen) | Nasopharyngeal swab | 20080731 |
| 258411007 | Nasopharyngeal aspirate (specimen) | Nasopharyngeal aspirate | 20080731 |
| 119364003 | Serum specimen (specimen) | Serum specimen | 20050131 |
| 119334006 | Sputum specimen (specimen) | Sputum specimen | 20080731 |
| 119339001 | Stool specimen (specimen) | Stool specimen | 20030731 |
| 258529004 | Throat swab (specimen) | Throat swab | 20080731 |
| 122877000 | Upper respiratory fluid specimen obtained by tracheal aspiration (specimen) | Upper respiratory fluid specimen obtained by tracheal aspiration | 20040731 |
| 122575003 | Urine specimen (specimen) | Urine specimen | 20080731 |
461911000124106 | Swab specimen from oropharynx (specimen) | Oropharyngeal swab | 20200731 |
2.4.2 Laboratory Tests
Laboratory tests can be performed to detect the presence of the COVID-19 virus and antibodies produced in response to this virus. The following SNOMED CT concepts can be used to record laboratory tests that may be performed during the investigation process.
| CV19-INV-LaboratoryTests | |||
|---|---|---|---|
| Concept id | Fully Specified Name | en-US Preferred Term | Effective Time |
| 122435008 | Measurement of viral antibody (procedure) | Measurement of viral antibody | 20100131 |
| 9718006 | Polymerase chain reaction analysis (procedure) | Polymerase chain reaction analysis | 20080731 |
| 118147004 | Viral nucleic acid assay (procedure) | Viral nucleic acid assay | 20020131 |
| 88667002 | Viral serologic study (procedure) | Viral serologic study | 20150131 |
Please refer to 2.4.1 Extension Concepts - Tests and Procedures for a list of known extension concepts.
2.4.3 Substances and Virus
Please refer to 2.4.1 Extension Concepts - Tests and Procedures for a list of known extension concepts. An antibody is a protective protein produced by the immune system in response to the presence of a foreign substance, called an antigen. The following antibody/antigen and virus organism concepts can be used to record the focus of a COVID-19 investigation.
| CV19-INV-SubstancesAndVirus | |||
|---|---|---|---|
| Concept id | Fully Specified Name | en-US Preferred Term | Effective Time |
| 840535000 | Antibody to severe acute respiratory syndrome coronavirus 2 (substance) | Antibody to SARS-CoV-2 | 20200131 |
| 840536004 | Antigen of severe acute respiratory syndrome coronavirus 2 (substance) | Antigen of SARS-CoV-2 | 20200131 |
| 840533007 | Severe acute respiratory syndrome coronavirus 2 (organism) | SARS-CoV-2 | 20200131 |
| 870361009 | Immunoglobulin G antibody to severe acute respiratory syndrome coronavirus 2 (substance) | SARS-CoV-2 IgG | 20200731 |
| 870362002 | Immunoglobulin M antibody to severe acute respiratory syndrome coronavirus 2 (substance) | SARS-CoV-2 IgM | 20200731 |
2.4.4 Laboratory Test Results
Laboratory test results are used to specify whether the Laboratory test focus was detected or not detected following the conducted laboratory test. The following qualifier values may be used for this purpose.
| CV19-INV-LabTestResults | |||
|---|---|---|---|
| Concept id | Fully Specified Name | en-US Preferred Term | Effective Time |
| 260373001 | Detected (qualifier value) | Detected | 20020131 |
| 260415000 | Not detected (qualifier value) | Not detected | 20020131 |
Please refer to 2.4.1 Extension Concepts - Tests and Procedures for a list of known extension concepts.
2.4.5 Other Investigations
Other investigative procedures - e.g. 719410009 | Consultation via video conference (procedure)| and 386472008 | Telephone consultation (procedure)| and 243791004 | Viral screening (procedure)| - may be performed to assess a COVID-19 patient. The following subset represents procedures that can be performed during the clinical assessment process.
| CV19-INV-Investigations | |||
|---|---|---|---|
Intensional Definition: |
Please refer to 2.4.1 Extension Concepts - Tests and Procedures for a list of known extension concepts.
Footnotes
Feedback
Overview
Content Tools
Apps