Allergy to [substance] (finding) v3 - DRAFT

Example:

• 294418003 |Allergy to phenol (finding)|
  

Expected classification (Agreed 21-Jan-2020):

• Classification results are expected to be consistent with the modeling in the Substance hierarchy.

Example:

293908005 |Allergy to chloral hydrate (finding)|

Chloral hydrate is a sedative and may not be well-represented by "Chloral derivative".

Expected classification (Agreed 21-Jan-2020):

• Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy. Concepts modeled using a modification should have the concept modeled using the base as an inferred parent if such a concept exists.
  • 782530003 |Allergy to chloral derivative (finding)| will be modeled with Causative agent = 418037002 |Chloral derivative (substance)| and will have the following inferred descendants:
    
    • 293908005 |Allergy to chloral hydrate (finding)|
      

Example:

• 294275005 |Allergy to opioid receptor antagonist (finding)|
  

Expected classification results (Agreed 21-Jan-2020):

• Classification results are expected to be consistent with the modeling in the Substance hierarchy for concepts modeled with an attribute value from the Substance hierarchy.

Role groupers in the Substance hierarchy will be inactivated in a future release and should not be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)

The following will be modelled with product role groupres

• 294606001 Allergy to antituberculosis agent (finding)
• 294605002 Allergy to antimycobacterial agent (finding)
• 294450008 Allergy to anthelmintic agent (finding)
• 294367002 Allergy to antiviral agent (finding)
• 294461000 Allergy to antibacterial drug (finding)

Example:

294367002 |Allergy to antiviral agent (finding)|

Expected classification results: NEEDS INTERNAL AGREEMENT

• Classification results are expected to be consistent with the modeling in the Substance hierarchy.
• TBD if there are any restrictions on which product roles can be used in modeling in this subhierarchy

Example:

• 782607004 |Allergy to phenothiazine derivative (finding)|

Expected classification (Agreed 21-Jan-2020):

• Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy.

No use case has been identified for use of this concept type for modeling in this subhierarchy. Structure groupers in the Product hierarchy should only exist as SD concepts with a corresponding concept in the Substance hierarchy; the corresponding concept in the Substance hierarchy should be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)

Body system groupers in both the Substance and Product hierarchies will be inactivated in a future release and should no longer be used for modeling in this hierarchy. (Agreed 21-Jan-2020)

Example:

• 294522005 |Allergy to ampicillin and cloxacillin (finding)|

Expected classification results: Needs input from Drugs WG - see DRUGS-865

• 294522005 |Allergy to ampicillin and cloxacillin (finding)| will be modeled with Causative agent = 346320003 |Product containing ampicillin and cloxacillin (medicinal product)| and will have the the following inferred parents:
  • 294506009 |Allergy to ampicillin (finding)| with Causative agent = 387170002 |Ampicillin (substance)|
  • 294501004 |Allergy to cloxacillin (finding)| with Causative agent = 373276005 |Cloxacillin (substance)|