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Overview

  • Fragments to be created as siblings of the intact/whole/entire substance
  • “Intact” should not be included when referring to the "entire substance" or "whole substance"; it is implied
  • Alpha and beta sub-units should be the children of the entire substance, where "nicked" substances and fragments should be the siblings
  • INN should be used for the Preferred Term where they exist

Modeling

Parent concept

Most distal appropriate descendant of 115668003 |Biological substance (substance)|

  • Exceptions: none
Semantic tag

(substance)

Definition status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

  • Exceptions: none

Attribute

|Has disposition| as appropriate

Naming Guidelines

FSN

Pattern:

  • X fragment (substance)
  • X subunit (substance)

For example,

  • Corticotrophin big fragment (substance)

  • Thyrotropin beta subunit (substance)

Preferred Term

Pattern:

  • X fragment

For example,

  • Corticotrophin big fragment
  • Thyrotropin beta subunit

Synonyms

Pattern: none identified


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