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Overview

Fragments

...

are created as siblings of the intact/whole/entire substance.

“Intact” should not be included when referring to the "entire substance" or "whole substance"; it is implied.

Alpha and beta sub-units should be the children of the entire substance, where "nicked" substances and fragments should be the siblings.

INN should be used for the Preferred Term where they exist.

Modeling

Parent concept

Most distal appropriate descendant of 115668003 |Biological substance (substance)|

Semantic tag

(substance)

Definition status
900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

Primitive

Attribute

|Has disposition| as appropriate

Naming

...

FSN

Pattern:

  • X fragment (substance)
  • X subunit (substance)

For example,

Corticotrophin
      • Corticotropin, big fragment (substance)|

      • Thyrotropin beta subunit (substance)

Preferred Term

Pattern:

  • X fragment

For example,

Corticotrophin
      • Corticotropin, big fragment
      • Thyrotropin beta subunit