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Link to the misaligned concept report
Overdose misaligned concept report 2021-Dec-14
Rules for generating descriptions:
Editorial guidelines for selection of Causative agent attribute value:
The following editorial guidelines apply to concepts in the International Release; editorial guidelines for concepts in national extensions may vary.
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Example:
- 295184007 |Morphine overdose (disorder)|
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Concepts representing substance modifications are exceptions and may be included if the overdose profile is significantly different from the substance base.
Exception examples:
- Liposome or lipid complex substances (e.g. 412088006 |Amphotericin B liposome (substance)|, 426490000 |Vincristine liposome (substance)|)
- Pegylated substance (e.g. 385544005 |Pegfilgrastim (substance)|, 770965008 |Pegvaliase (substance)|)
- Salt forms (e.g. 273948005 |Chloral hydrate (substance)|, 396063006 |Fluphenazine decanoate (substance)|)
Example:
- 296136008 |Chloral hydrate overdose (disorder)|
- 296213007 |Fluphenazine decanoate overdose (disorder)|
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Overdose concepts representing a disposition grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.
Example:
- 297053006 |Overdose of angiotensin-converting-enzyme inhibitors (disorder)|
- 296515004 |Opiate antagonist overdose (disorder)|
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Overdose concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release.
Example:
- 297006008 |Diuretic overdose (disorder)|
- 295217003 |Non-steroidal anti-inflammatory overdose (disorder)|
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Overdose concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.
Example:
- 295188005 |Pethidine analog overdose (disorder)|
- 1155996000 |Phenothiazine and/or phenothiazine derivative overdose (disorder)|
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Overdose concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release.
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Medicinal product form-only
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The following types of groupers are out of scope; existing concepts have been inactivated or will be addressed in future release:
- Groupers based on more than one role (e.g. 292722006 |Chelating agents and antidotes adverse reaction (disorder)|)
- Groupers based on body system or intended site or route of administration (e.g. 292548001 |Drug groups primarily affecting respiratory system adverse reaction (disorder)|) or 417895009 |Topical agent adverse reaction (disorder)|)
- Groupers based on disposition, role, or structure combined with an individual substance (e.g. 287177000 |Sulfonamide/trimethoprim reaction (disorder)| or 292513008 |Methyldopa and diuretic adverse reaction (disorder)|)
- Groupers based on "combined" or "compound" substances (e.g. 292983008 |Combined penicillin preparation adverse reaction (disorder)| or 293358005 |Compound iron preparations adverse reaction (disorder)|)
- Groupers based on disposition or structure combined with intended site or route of administration (e.g. 433494006 |Adverse effect of oral diphosphonate (disorder)|)
Rules for description generation:
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JIRA ticket for implementation:
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