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Laterality' attribute is optional and is only applicable for an anatomical entity that is lateralizable, e.g. limb, hand. More information can be found in the Editorial Guide chapter  5. Laterality (draft)

Concept in [ ] should be replaced by other concept for new model. 

Entire named body region:

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'Body structure (body structure)'
and ('All or part of (attribute)' some 'Entire skin (body structure)')
and ('All or part of (attribute)' some '[Entire hand] (body structure)')
and ('Laterality (attribute)' some 'Side (qualifier value)')
SubClassOf '[Skin structure of [ hand] (body structure)'

Skin structure of part of [body region]:

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'Body structure (body structure)'
and ('All or part of (attribute)' some 'Entire skin (body structure)')
and ('All or part of (attribute)' some ('Regional part of (attribute)' some '[Entire hand] (body structure)'))
and ('Laterality (attribute)' some 'Side (qualifier value)')
SubClassOf '[Skin structure of part of [ hand] (body structure)'