A.5 Exclusion and Not Equals - Valid Expressions

Expression Constraint	Valid Expression¹
	Precoordinated	Postcoordinated
<< 19829001 \|Disorder of lung\| MINUS << 301867009 \|Edema of trunk\|	372146004 \|Acute chest syndrome\|	27819004 \|Pulmonary ossification\| : { 116676008 \|Associated morphology\| = 18115005 \|Pathologic calcification\| , 363698007 \|Finding site\| = 31094006 \|Structure of lobe of lung\| }
	413839001 \|Chronic lung disease\|
<< 19829001 \|Disorder of lung\| MINUS ^ 700043003 \|Example problem list concepts reference set\|	233613009 \|Fungal pneumonia\|	27819004 \|Pulmonary ossification\| : { 116676008 \|Associated morphology\| = 18115005 \|Pathologic calcification\| , 363698007 \|Finding site\| = 31094006 \|Structure of lobe of lung\| }
< 404684003 \|Clinical finding\| : 116676008 \|Associated morphology\| = ((<< 56208002 \|Ulcer\| AND << 50960005 \|Hemorrhage\| ) MINUS << 26036001 \|Obstruction\| )	15902003 \|Gastric ulcer with hemorrhage\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 55075001 \|Bleeding ulcer\| , 363698007 \|Finding site\| = 14374004 \|Structure of lymphatic vessel of esophagus\| }
< 404684003 \|Clinical finding\| : 116676008 \|Associated morphology\| != << 26036001 \|Obstruction\|	233613009 \|Fungal pneumonia\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 26036001 \|Obstruction\| , 363698007 \|Finding site\| = 422897007 \|Vascular structure of stomach\| } { 116676008 \|Associated morphology\| = 45771005 \|Acute bleeding ulcer\| , 363698007 \|Finding site\| = 422897007 \|Vascular structure of stomach\| }
	46708007 \|Acute gastric ulcer with hemorrhage AND obstruction\|
< 404684003 \|Clinical finding\| : [0..0] 116676008 \|Associated morphology\| = << 26036001 \|Obstruction\|	233613009 \|Fungal pneumonia\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 55075001 \|Bleeding ulcer\| , 363698007 \|Finding site\| = 14374004 \|Structure of lymphatic vessel of oesophagus\| }
	15902003 \|Gastric ulcer with hemorrhage\|
< 404684003 \|Clinical finding\| : [0..0] 116676008 \|Associated morphology\| != << 26036001 \|Obstruction\|	244815007 \|Pyloric obstruction\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 26036001 \|Obstruction\| , 363698007 \|Finding site\| = 314600001 \|Choledochoenterostomy stoma\| }
	84906002 \|Local cyanosis\|
< 404684003 \|Clinical finding\| : [0..0] 116676008 \|Associated morphology\| != << 26036001 \|Obstruction\| AND [1..*] 116676008 \|Associated morphology\| = << 26036001 \|Obstruction\|	244815007 \|Pyloric obstruction\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 26036001 \|Obstruction\| , 363698007 \|Finding site\| = 314600001 \|Choledochoenterostomy stoma\| }

Footnotes
Ref	Notes
1	Where necessary, these examples make some assumptions about the membership of the example reference sets.

Expression Constraint	Valid Expression¹
	Precoordinated	Postcoordinated
<< 19829001 \|Disorder of lung\| MINUS << 301867009 \|Edema of trunk\|	372146004 \|Acute chest syndrome\|	27819004 \|Pulmonary ossification\| : { 116676008 \|Associated morphology\| = 18115005 \|Pathologic calcification\| , 363698007 \|Finding site\| = 31094006 \|Structure of lobe of lung\| }
	413839001 \|Chronic lung disease\|
<< 19829001 \|Disorder of lung\| MINUS ^ 700043003 \|Example problem list concepts reference set\|	233613009 \|Fungal pneumonia\|	27819004 \|Pulmonary ossification\| : { 116676008 \|Associated morphology\| = 18115005 \|Pathologic calcification\| , 363698007 \|Finding site\| = 31094006 \|Structure of lobe of lung\| }
< 404684003 \|Clinical finding\| : 116676008 \|Associated morphology\| = ((<< 56208002 \|Ulcer\| AND << 50960005 \|Hemorrhage\| ) MINUS << 26036001 \|Obstruction\| )	15902003 \|Gastric ulcer with hemorrhage\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 55075001 \|Bleeding ulcer\| , 363698007 \|Finding site\| = 14374004 \|Structure of lymphatic vessel of esophagus\| }
< 404684003 \|Clinical finding\| : 116676008 \|Associated morphology\| != << 26036001 \|Obstruction\|	233613009 \|Fungal pneumonia\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 26036001 \|Obstruction\| , 363698007 \|Finding site\| = 422897007 \|Vascular structure of stomach\| } { 116676008 \|Associated morphology\| = 45771005 \|Acute bleeding ulcer\| , 363698007 \|Finding site\| = 422897007 \|Vascular structure of stomach\| }
	46708007 \|Acute gastric ulcer with hemorrhage AND obstruction\|
< 404684003 \|Clinical finding\| : [0..0] 116676008 \|Associated morphology\| = << 26036001 \|Obstruction\|	233613009 \|Fungal pneumonia\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 55075001 \|Bleeding ulcer\| , 363698007 \|Finding site\| = 14374004 \|Structure of lymphatic vessel of oesophagus\| }
	15902003 \|Gastric ulcer with hemorrhage\|
< 404684003 \|Clinical finding\| : [0..0] 116676008 \|Associated morphology\| != << 26036001 \|Obstruction\|	244815007 \|Pyloric obstruction\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 26036001 \|Obstruction\| , 363698007 \|Finding site\| = 314600001 \|Choledochoenterostomy stoma\| }
	84906002 \|Local cyanosis\|
< 404684003 \|Clinical finding\| : [0..0] 116676008 \|Associated morphology\| != << 26036001 \|Obstruction\| AND [1..*] 116676008 \|Associated morphology\| = << 26036001 \|Obstruction\|	244815007 \|Pyloric obstruction\|	64572001 \|Disease\| : { 116676008 \|Associated morphology\| = 26036001 \|Obstruction\| , 363698007 \|Finding site\| = 314600001 \|Choledochoenterostomy stoma\| }

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A.5 Exclusion and Not Equals - Valid Expressions