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StatusReady for implementation
Version

2.7

Version in PROD2.0

Descriptions:

Termdescription typeLanguage/acceptabilityLanguage/acceptabilityCase Significance

Allergy to [substance or product] (finding)

FSNus:Pgb:Pci

Allergy to [substance or product]

SYNus:Pgb:Pci
[substance or product] allergySYNus:Agb:Aci


Concept model:

Attribute Group CardinalityAttribute CardinalityAttribute in Group CardinalityAttributeValue

1..10..0

116680003 |Is a (attribute)|

420134006 |Propensity to adverse reactions (finding)|

1..1
1..1

246075003 |Causative agent (attribute)|


<  105590001 |Substance (substance)|  OR <  373873005 |Pharmaceutical / biologic product (product)|


1..1

719722006 |Has realization (attribute)|

<<  472964009 |Allergic process (qualifier value)|

Definition status:  


900000000000073002 |Defined (core metadata concept)|

Applies to:

<  609328004 |Allergic disposition (finding)|

EDITORIAL GUIDELINES for Causative agent (attribute):

Hierarchy

Concept type

Allowed

Exception

Examples and Notes

SubstanceBase substanceyesnone

Allergy concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.

Example:

  • 294418003 |Allergy to phenol (finding)|

Expected classification (Agreed 21-Jan-2020):

  • Classification results are expected to be consistent with the modeling in the Substance hierarchy.
SubstanceModificationnoyes

Example:

293908005 |Allergy to chloral hydrate (finding)|

Chloral hydrate is a sedative and may not be well-represented by "Chloral derivative".

Expected classification (Agreed 21-Jan-2020):

  • Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy. Concepts modeled using a modification should have the concept modeled using the base as an inferred parent if such a concept exists.
    • 782530003 |Allergy to chloral derivative (finding)| will be modeled with Causative agent = 418037002 |Chloral derivative (substance)| and will have the following inferred descendants:
      • 293908005 |Allergy to chloral hydrate (finding)|
SubstanceDisposition grouperyesnone

Example:

  • 294275005 |Allergy to opioid receptor antagonist (finding)|

Expected classification results (Agreed 21-Jan-2020):

  • Classification results are expected to be consistent with the modeling in the Substance hierarchy for concepts modeled with an attribute value from the Substance hierarchy.
SubstanceStructure grouperyesnone

Example:

  • 782607004 |Allergy to phenothiazine derivative (finding)|

Expected classification (Agreed 21-Jan-2020):

  • Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy.
SubstanceRole groupernonone

Role groupers in the Substance hierarchy will be inactivated in a future release and should not be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)

ProductDisposition groupernononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Disposition groupers in the Product hierarchy should only exist as SD concepts with a corresponding concept in the Substance hierarchy; the corresponding concept in the Substance hierarchy should be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)
ProductStructure groupernonone

No use case has been identified for use of this concept type for modeling in this subhierarchy. Structure groupers in the Product hierarchy should only exist as SD concepts with a corresponding concept in the Substance hierarchy; the corresponding concept in the Substance hierarchy should be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)


ProductRole grouperyesnone

Example:

417930000 |Allergy to adhesive agent (finding)|

Expected classification results: NEEDS INTERNAL AGREEMENT

ProductMedicinal product-containingyesnone

Example:

  • 294522005 |Allergy to ampicillin and cloxacillin (finding)|

Expected classification results: NEEDS INTERNAL AGREEMENT

  • 294650000 |Allergy to vaccine product containing Mumps orthorubulavirus antigen (finding)|

https://confluence.ihtsdotools.org/display/IAP/Allergy+to+X+vaccine

ProductMedicinal product-onlynononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product-containing concepts can be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)
ProductMedicinal product form-containingnononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)
ProductMedicinal product form-onlynononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)
ProductClinical drugnononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)

Template language

420134006 |Propensity to adverse reactions (finding)|  : [[~1..1 @rolegroup]] { [[~1..1]]  719722006 |Has realization (attribute)|  =  472964009 |Allergic process (qualifier value)| , [[~1..1]]  246075003 |Causative agent (attribute)|  = [[ +id (<  105590001 |Substance (substance)|  OR <  373873005 |Pharmaceutical / biologic product (product)| ) @causative]] }

 Misalignment report:

https://docs.google.com/spreadsheets/d/1CUWI2KYdfjj2MuFTLif1AzCk8BaFYpNN0738F5gJvdk/edit#gid=0

Rules for description generation:

  1. Remove the semantic tag, e.g. (body structure)
  2. Remove 'Structure of' from [body structure] if term starts with 'Structure of'   e.g. 709530002|Structure of phalanx of hand (body structure)|
  3. Remove 'structure' from [body structure] if term contains 'structure', e.g. 69536005|Head structure (body structure)|   24097009|Bone structure of hand (body structure)|

JIRA ticket for implementation:

INFRA-11601 - Getting issue details... STATUS


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