Descriptions:
| Term | description type | Language/acceptability | Langauge/acceptability | Case significance |
|---|---|---|---|---|
Anaphylaxis caused by [agent] (disorder) | FSN | us:P | gb:P | ci |
Anaphylaxis caused by [agent] | SYN | us:P | gb:P | ci |
Concept model:
| Attribute Cardinality | Attribute | Value | role group number | Role group cardinality |
|---|---|---|---|---|
| 1..1 | 0 | N/A | ||
| 1..1 | 0 | N/A | ||
| 1..1 | 1 | 1..1 | ||
| 1..1 |
Definition status:
900000000000073002 |Defined (core metadata concept)|
Template Language
281647001 |Adverse reaction (disorder)|: [[~1..1]] { [[~0..1]] 363698007 |Finding site (attribute)| = [[+id(< 123037004 |Body structure (body structure)|) @site]], [[~1..1]] 246075003 |Causative agent (attribute)| = [[+id( << 105590001 |Substance (substance)| OR << 373873005 |Pharmaceutical / biologic product (product)| OR << 260787004 |Physical object (physical object)| OR << 78621006 |Physical force (physical force)|) @agent]] }
Applies to:
<< 417516000 |Anaphylaxis caused by substance (disorder)|
Editorial guidelines for selection of Causative agent attribute value:
The following editorial guidelines apply to concepts in the International Release; editorial guidelines for concepts in national extensions may vary.
| Concept type | Allowed | Examples and Notes (Note: Examples are existing concepts and may not reflect the terming patterns described in the template.) |
|---|---|---|
| Substance base | yes | Concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification (Agreed 21-Jan-2020):
|
| Substance modification | yes, only if identified as accepted exception | Adverse reaction concepts representing a substance modification should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Concepts representing substance modifications are exceptions and may be included if the adverse reaction profile is significantly different from the substance base. Exception examples: None identified |
| Multiple substance | yes | Adverse reaction concepts representing multiple substances should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|; preferentially modeling with the base rather than a modification unless the adverse reaction profile is significantly different from the substance base. Example:
Expected classification (Agreed 21-Jan-2020):
|
| Disposition grouper | yes | Adverse reaction concepts representing a disposition grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification results (Agreed 21-Jan-2020):
|
| Role grouper | no | Adverse reaction concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Note that role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release. Example:
Expected classification results (Agreed 21-Jan-2020):
|
| Structure grouper | yes | Adverse reaction concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification (Agreed 21-Jan-2020):
|
Rules for description generation:
- For the FSN, align terming and case sensitivity with the FSN for the concept that is selected as the attribute value, excluding the semantic tag.
- For the PT, align terming and case sensitivity with the US and GB PT for the concept that is selected as the attribute value.
- In cases where neither the US or GB PT matches the FSN, excluding the semantic tag, a synonym corresponding to the FSN is required unless explicitly identified as an exception.
- Additional synonyms "[agent] adverse reaction" should be added. Other synonyms are not allowed unless explicitly identified as an exception.