Poisoning caused by [substance/Product] (disorder) - v1.0

Status	For review
Version	0.7

Descriptions:

Term	description type	Language/acceptability	Language/acceptability	Case significance
[Accidental/Intentional] Poisoning caused by [agent] due to [event] (disorder)	FSN	us:P	gb:P	ci
[Accidental/Intentional] Poisoning caused by [agent] due to [event]	SYN	us:P	gb:P	ci
[Accidental/Intentional] [Agent] poisoning due to [event]	SYN	us:A	gb:A	ci

Concept model:

Attribute cardinality	Attribute cardinality in role group	Attribute	Value
1..1	0..0	116680003 \|Is a (attribute)\|	75478009 \|Poisoning (disorder)\|
0..1	0..1	263502005 \|Clinical course (attribute)\|	< 288524001 \|Courses (qualifier value)\|
0..1	0..1	42752001 \|Due to (attribute)\|	<< 1148742001 \|Intentional event (event)\| OR << 418019003 \|Accidental event (event)\| OR << 418715001 \|Exposure to potentially harmful entity (event)\|
1..1	1..1	246075003 \|Causative agent (attribute)\|	[agent] << 105590001 \|Substance (substance)\| OR << 373873005 \|Pharmaceutical / biologic product (product)\|
	0..1	363698007 \|Finding site (attribute)\|	< 123037004 \|Body structure (body structure)\|
	0..1	116676008 \|Associated morphology (attribute)\|	< 49755003 \|Morphologically abnormal structure (morphologic abnormality)\|

Definition status:

900000000000073002 |Defined (core metadata concept)|

Applies to

Poisoning caused by substance or product, excluding concepts of types: "Food poisoning" and "Poisoning by organism" (the applicability of this template for these concepts needs to be evaluated) as well as "Overdose", and "Intoxication" (which will have their own templates):

(((<< 7895008 |Poisoning caused by drug AND/OR medicinal substance (disorder)| ) : [0..0] 42752001 |Due to (attribute)| = 781249001 |Consumption of contaminated food (event)| AND [0..0] 246075003 |Causative agent (attribute)| = << 410607006 |Organism (organism)| ) OR (( << 441952005 |Poisoning caused by chemical substance (disorder)| ) : [0..0] 42752001 |Due to (attribute)| = 781249001 |Consumption of contaminated food (event)| AND [0..0] 246075003 |Causative agent (attribute)| = << 410607006 |Organism (organism)| )) MINUS (<< 1149322001 |Intoxication (disorder)| OR << 1149222004 |Overdose (disorder)| )

Template Language

75478009 |Poisoning (disorder)| :
[[~0..1]] {[[~0..1]] 263502005 |Clinical course (attribute)| = [[ +id ( < 288524001 |Courses (qualifier value)| ) @course]]},
[[~0..1]] {[[~0..1]] 42752001 |Due to (attribute)| = [[+id ( << 1148742001 |Intentional event (event)| OR << 418019003 |Accidental event (event)| OR << 418715001 |Exposure to potentially harmful entity (event)) @dueto ]]}, [[~1..1 @rolegroup]]{ [[~1..1]] 246075003| Causative agent (attribute) |= [[+id ( << 105590001| Substance (substance) |OR << 373873005| Pharmaceutical / biologic product (product) |) @agent]], [[~0..1]] 363698007| Finding site (attribute) |= [[+id ( < 123037004| Body structure (body structure) |) ]], [[~0..1]] 116676008| Associated morphology (attribute) |= [[+id ( < 49755003| Morphologically abnormal structure (morphologic abnormality) |) ]]}|

Link to the misaligned concept report

Rules for generating descriptions:

Apply General rules for generating descriptions for templates
Remove the word 'event' and semantic tag from the value of |Due to|

EDITORIAL GUIDELINES for Causative agent (attribute):

Hierarchy	Concept type	Allowed	Exception	Examples and Notes
Substance	Base	yes	none	Poisoning concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 \|Substance (substance)\|. Examples: 13503000 \|Poisoning caused by naloxone (disorder)\| 30138004 \|Poisoning caused by ether (disorder)\| Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the Substance hierarchy.
Substance	Modification	no	yes	Poisoning concepts representing a substance modification should be modeled using a Causative agent that is a descendant of 105590001 \|Substance (substance)\|. Concepts representing substance modifications are exceptions and may be included if the poisoning profile is significantly different from the substance base. Exception examples: Chemical element with multiple modifications (e.g. 422232005 \|Calcium lactate gluconate (substance)\| Liposome or lipid complex substances (e.g. 412088006 \|Amphotericin B liposome (substance)\|, 426490000 \|Vincristine liposome (substance)\|) Pegylated substance (e.g. 385544005 \|Pegfilgrastim (substance)\|, 770965008 \|Pegvaliase (substance)\|) Salt forms (e.g. 273948005 \|Chloral hydrate (substance)\|, 396063006 \|Fluphenazine decanoate (substance)\|) Examples of exception: 62942003 \|Tetraethyl pyrophosphate poisoning (disorder)\|
Substance	Structure grouper	yes	none	Poisoning concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 \|Substance (substance)\|. Examples: 1153528004 \|Poisoning caused by substance with ether structure (disorder)\| Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the Substance hierarchy.
Substance	Disposition grouper	yes	none	Poisoning concepts representing a disposition grouper should be modeled using a Causative agent that is a descendant of 105590001 \|Substance (substance)\|. Examples: 9291000 \|Poisoning caused by monoamine oxidase inhibitor (disorder)\| Classification results are expected to reflect that the adverse reaction concepts are descendants of the appropriate disposition grouper based on the modeling of the 726542003 \|Has disposition (attribute)\| attribute in the substance hierarchy.
Substance	Role grouper	no	none	Currently poisoning concepts representing a role grouper are modeled using a Causative agent that is a descendant of 105590001 \|Substance (substance)\|. Note that role groupers will be transitioned to the 763158003 \|Medicinal product (product)\| hierarchy in a future release.
Product	Structure grouper	no	none	No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product-containing concepts can be used for modeling in this subhierarchy.
Product	Disposition grouper	no	none	No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product-containing concepts can be used for modeling in this subhierarchy.
Product	Role grouper	yes	none	Examples to be added - pending implementation of roles and products as causative agents
Product	Medicinal product-containing	yes	none	Examples to be added - pending implementation of roles and products as causative agents
Product	Medicinal product-only	no	none	No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product-containing concepts can be used for modeling in this subhierarchy.
Product	Medicinal product form-containing	no	none	No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy.
Product	Medicinal product form-only	no	none	No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy.
Product	Clinical drug	no	none	No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy.

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