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Descriptions:
| Term | description type | Language/acceptability | Langauge/acceptability | Case significance |
|---|---|---|---|---|
substance or product overdose (disorder) | FSN | us:P | gb:P | ci |
Overdose | SYN | us:P | gb:P | ci |
Concept model:
| Attribute Cardinality | Attribute | Value | Role group number | Role group cardinality |
|---|---|---|---|---|
| 1..1 | 0 | n/a | ||
| 0..1 | 0 | 0..1 | ||
| 0..1 | 0 | 0..1 | ||
| 0..1 | 0 | 0..1 |
Definition status:
900000000000073002 |Defined (core metadata concept)|
Template Language
Applies to:
<< 1149222004 |Overdose (disorder)|
Editorial guidelines for selection of Causative agent attribute value:
The following editorial guidelines apply to concepts in the International Release; editorial guidelines for concepts in national extensions may vary.
| Causative agent type | Allowed | Examples and Notes (Note: Examples are existing concepts and may not reflect the terming patterns described in the template.) |
|---|---|---|
| Substance base | yes | Overdose concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification:
|
| Substance modification | no, unless documented as exception | Overdose concepts representing a substance modification should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Concepts representing substance modifications are exceptions and may be included if the overdose profile is significantly different from the substance base. Exception examples:
Example:
Expected classification:
|
| Multiple substance | yes | Adverse reaction concepts representing multiple substances should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|; preferentially modeling with the base rather than a modification unless the adverse reaction profile is significantly different from the substance base. Example:
Expected classification (Agreed 21-Jan-2020):
|
| Disposition grouper | yes | Overdose concepts representing a disposition grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification results:
|
| Role grouper | yes | Overdose concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Note that role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release. Example:
Expected classification results (to be revised when concepts are remodeled using Medicinal product ):
|
| Structure grouper | yes | Overdose concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification (Agreed 21-Jan-2020):
|
| Descendant of 373873005 |Pharmaceutical / biologic product (product)| | no, unless documented as exception | Exceptions: None identified |
The following types of groupers are out of scope; existing concepts have been inactivated or will be addressed in future release:
- Groupers based on more than one role (e.g. 292722006 |Chelating agents and antidotes adverse reaction (disorder)|)
- Groupers based on body system or intended site or route of administration (e.g. 292548001 |Drug groups primarily affecting respiratory system adverse reaction (disorder)|) or 417895009 |Topical agent adverse reaction (disorder)|)
- Groupers based on disposition, role, or structure combined with an individual substance (e.g. 287177000 |Sulfonamide/trimethoprim reaction (disorder)| or 292513008 |Methyldopa and diuretic adverse reaction (disorder)|)
- Groupers based on "combined" or "compound" substances (e.g. 292983008 |Combined penicillin preparation adverse reaction (disorder)| or 293358005 |Compound iron preparations adverse reaction (disorder)|)
- Groupers based on disposition or structure combined with intended site or route of administration (e.g. 433494006 |Adverse effect of oral diphosphonate (disorder)|)
- Groupers based on disposition combined with role (e.g. 292265006 |Dopaminergic drug used in parkinsonism adverse reaction (disorder)|)
Rules for description generation:
- For the FSN, align terming and case sensitivity with the FSN for the concept that is selected as the attribute value, excluding the semantic tag.
- For the PT, align terming and case sensitivity with the US and GB PT for the concept that is selected as the attribute value.
- In cases where neither the US or GB PT matches the FSN, excluding the semantic tag, a synonym corresponding to the FSN is required unless explicitly identified as an exception.
- Additional synonyms "[agent] adverse reaction" should be added. Other synonyms are not allowed unless explicitly identified as an exception.