Descriptions:
| Term | description type | Language/acceptability | Langauge/acceptability | Case significance |
|---|---|---|---|---|
Allergy to [substance] (finding) | FSN | us:P | gb:P | ci |
Allergy to [substance] | SYN | us:P | gb:P | ci |
Concept model:
| Attribute Cardinality | Attribute | Value | Role group cardinality |
|---|---|---|---|
| 1..* | N/A | ||
| 1..1 | [substance] | 1..1 | |
| 1..1 |
Definition status:
900000000000073002 |Defined (core metadata concept)|
Applies to:
<<
419199007 |Allergy to substance (disorder)|
Template language
419199007 |Allergy to substance (finding)| : [[~1..1 @rolegroup]] { [[~1..1]] 719722006 |Has realization (attribute)| = 472964009 |Allergic process (qualifier value)| , [[~1..1]] 246075003 |Causative agent (attribute)| = [[ +id (<< 105590001 |Substance (substance)| ) @causative]] }
Misalignment report:
https://docs.google.com/spreadsheets/d/1CUWI2KYdfjj2MuFTLif1AzCk8BaFYpNN0738F5gJvdk/edit#gid=0
Rules for description generation:
- Remove the semantic tag, e.g. (body structure)
- Remove 'Structure of' from [body structure] if term starts with 'Structure of' e.g. 709530002|Structure of phalanx of hand (body structure)|
- Remove 'structure' from [body structure] if term contains 'structure', e.g. 69536005|Head structure (body structure)| 24097009|Bone structure of hand (body structure)|
JIRA ticket for implementation:
INFRA-2549 - Getting issue details... STATUS
Exceptions:
There are few exceptions in modeling the causative agent attribute for descendants of the 419199007 |Allergy to substance (finding)| in comparison to the general template guidelines:
- 788802000|Allergy to cetuximab (finding)|
- The allergy is to alpha-gal substance in a product containing cetuximab.
- 432807008 |Pollen-food allergy (finding)|
- This is a contact food allergy that occurs in patients with pollen allergy when ingesting raw fruits, vegetables and some tree nuts. Symptoms are caused by a heat-labile protein in fruits, vegetables, and nuts that cross-reacts with proteins in aeroallergens.
- 293908005 |Allergy to chloral hydrate (finding)|
- In general, concepts in the 419199007 |Allergy to substance (finding)| sub-hierarchy are modeled with the base substance and not its modification. Chloral hydrate is an exception to this rule.
Please note that for the first two: since it is hard to fully define these concepts, they have been left as primitive concepts.