Page properties |
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Status | Ready for implementation |
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Version | 2.7 |
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Version in PROD | 2.0 |
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Descriptions:
Term | description type | Language/acceptability | LangaugeLanguage/acceptability | Case significanceSignificance |
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Allergy to [substance or product] (finding) | FSN | us:P | gb:P | ci |
Allergy to [substance or product] | SYN | us:P | gb:P | ci |
[substance or product] allergy | SYN | us:A | gb:A | ci |
Concept model:
Attribute Group Cardinality | Attribute Cardinality | Attribute in Group Cardinality | Attribute | Value | Role group cardinality |
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| 1..1 | 0 | 1.. | *0 |
Scg expression |
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116680003|Is a (attribute)| |
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Scg expression |
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420134006|Propensity to adverse reactions (finding)| |
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N/A1..1 |
| 1..1 |
Scg expression |
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246075003|Causative agent (attribute)| |
| | [agent] | << 105590001|Substance (substance)| OR |
| <<< 373873005|Pharmaceutical / biologic product (product)| |
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| 1..1 | 1..1 |
Scg expression |
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719722006|Has realization (attribute)| |
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Scg expression |
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<< 472964009|Allergic process (qualifier value)| |
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Definition status:
Scg expression |
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900000000000073002|Defined (core metadata concept)| |
Applies to:
Scg expression |
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<<< 419199007609328004 |AllergyAllergic todisposition substance (disorderfinding)| |
EDITORIAL GUIDELINES for Causative agent (attribute):
Hierarchy | Concept type | Allowed | Exception | Examples and Notes |
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Substance | Base substance | yes | none | Allergy concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example: - 294418003 |Allergy to phenol (finding)|
Expected |
classification: NEEDS INTERNAL AGREEMENTclassification (Agreed 21-Jan-2020):
- Classification results are expected to be consistent with the modeling in the Substance hierarchy
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and with other existing concepts in the subhierarchy |
Substance | Modification | no | yes | Example: 293908005 |Allergy to chloral hydrate (finding)| Chloral hydrate is a sedative and may not be well-represented by "Chloral derivative".
Expected classification |
: NEEDS INTERNAL AGREEMENT(Agreed 21-Jan-2020):
- Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy. Concepts modeled using a modification should have the concept modeled using the base as an inferred parent if such a concept exists.
- 782530003 |Allergy to chloral derivative (finding)| will be modeled with Causative agent = 418037002 |Chloral derivative (substance)| and will have the following inferred descendants:
- 293908005 |Allergy to chloral hydrate (finding)|
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Substance | Disposition grouper | yes | none | Example: - 294275005 |Allergy to opioid receptor antagonist (finding)|
Expected classification |
results: NEEDS INTERNAL AGREEMENTresults (Agreed 21-Jan-2020): - Classification results are expected to be consistent with the modeling in the Substance hierarchy
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and with other existing concepts in the subhierarchy.Product | Disposition grouper | no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Disposition groupers in the Product hierarchy should only exist as SD concepts with a corresponding concept in the Substance hierarchy; the corresponding concept in the Substance hierarchy should be used for modeling in this subhierarchy. NEEDS INTERNAL AGREEMENT- for concepts modeled with an attribute value from the Substance hierarchy.
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Substance | Structure grouper | yes | none | Example: - 782607004 |Allergy to phenothiazine derivative (finding)|
Expected classification (Agreed 21-Jan-2020): - Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy.
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Substance | Role grouper | no | none | Role groupers in the Substance hierarchy will be inactivated in a future release and should not be used for modeling in this subhierarchy. |
NEEDS INTERNAL AGREEMENT(Agreed 21-Jan-2020) |
Product |
Role Substance | Structure grouper | yes | none | Example: - 782607004 |Allergy to phenothiazine derivative (finding)|
Expected classification: NEEDS INTERNAL AGREEMENT - Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy.
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yes | none | Example: 294367002 |Allergy to antiviral agent (finding)|
Expected classification results: NEEDS INTERNAL AGREEMENT - Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy.
- TBD if there are any restrictions on which product roles can be used in modeling in this subhierarchy
| no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Disposition groupers in the Product hierarchy should only exist as SD concepts with a corresponding concept in the Substance hierarchy; the corresponding concept in the Substance hierarchy should be used for modeling in this subhierarchy. (Agreed 21-Jan-2020) |
Product | Structure grouper | no | none | No use case has been identified for use of this concept |
type for type for modeling in this subhierarchy. |
Structure Structure groupers in the Product hierarchy should only exist as SD concepts with a corresponding concept in the Substance hierarchy; the corresponding concept in the Substance hierarchy should be used for modeling in this subhierarchy. |
NEEDS INTERNAL AGREEMENT(Agreed 21-Jan-2020)
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Product |
or SubstanceBody system noBody system groupers in both the Substance and Product hierarchies will be inactivated in a future release and should no longer be used for modeling in this hierarchy. NEEDS INTERNAL AGREEMENTExample: 417930000 |Allergy to adhesive agent (finding)| - Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy.
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Product | Medicinal product-containing | yes | none | Example: - 294522005 |Allergy to ampicillin and cloxacillin (finding)|
Expected classification results: |
NEEDS 294522005 294506009 |Allergy to ampicillin (finding)| with Causative agent = 387170002 |Ampicillin (substance)|294501004 |Allergy to cloxacillin (finding)| with Causative agent = 373276005 |Cloxacillin (substance)| ampicillin and cloxacillin (finding)| will be modeled with Causative agent = 346320003 |Product containing ampicillin and cloxacillin (medicinal product)| and will have the the following inferred parents:
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Product | Medicinal product-only | no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
NEEDS INTERNAL AGREEMENTMedicinal product-containing concepts can be used for modeling in this subhierarchy. (Agreed 21-Jan-2020)
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Product | Medicinal product form-containing |
yesno | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy. |
NEEDS INTERNAL AGREEMENT(Agreed 21-Jan-2020) |
Product | Medicinal product form-only | no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy. |
NEEDS INTERNAL AGREEMENT(Agreed 21-Jan-2020) |
Product | Clinical drug | no | none | No use case has been identified for use of this concept |
type type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy. |
NEEDS INTERNAL AGREEMENT Template language
Scg expression |
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419199007 420134006|AllergyPropensity to substanceadverse reactions (finding)| : [[~1..1 @rolegroup]] { [[~1..1]] 719722006 |Has realization (attribute)| = 472964009 |Allergic process (qualifier value)|, [[~1..1]] 246075003 |Causative agent (attribute)| = [[ +id (< 105590001 |Substance (substance)| OR < 373873005 |Pharmaceutical / biologic product (product)|) @causative]] } |
Misalignment report:
https://docs.google.com/spreadsheets/d/1CUWI2KYdfjj2MuFTLif1AzCk8BaFYpNN0738F5gJvdk/edit#gid=0
Rules for description generation:
- Remove the semantic tag, e.g. (body structure)
- Remove 'Structure of' from [body structure] if term starts with 'Structure of' e.g. 709530002|Structure of phalanx of hand (body structure)|
- Remove 'structure' from [body structure] if term contains 'structure', e.g. 69536005|Head structure (body structure)| 24097009|Bone structure of hand (body structure)|
JIRA ticket for implementation:
Jira |
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server | IHTSDO JIRA |
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serverId | b202d822-d767-33be-b234-fec5accd5d8c |
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key | INFRA-11601 |
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