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StatusIn progressReady for implementation
Version1.0.1


Descriptions:

Termdescription typeLanguage/acceptabilityLanguage/acceptabilityCase significanceSignificance
[Accidental/Intentional] Poisoning caused by [substance or product[agent] due to [event] (disorder)FSNus:Pgb:Pci
Poisoning caused by [substance or product[Accidental/Intentional] Poisoning caused by [agent] due to [event
SYNus:Pgb:Pci
[substance or product] poisoningAccidental/Intentional] [Agent] poisoning due to [event]SYNus:Agb:Aci

Concept model:

<<1148742001Intentional event (event)| OR << 418019003 |Accidental event *0<<<<37782003Damage
Attribute cardinalityAttribute cardinality in role groupAttributeValue
1..10..0


Scg expression
116680003 |Is a (attribute)|



Scg expression
75478009 |Poisoning (disorder)|


0..10..1


Scg expression
263502005 |Clinical course (attribute)|



Scg expression
< 288524001 |Courses (qualifier value)|


0..10..1


Scg expression
42752001 |Due to (attribute)|



Scg expression
< 
272379006 |
Event (event)|


0..21..1


Scg expression
246075003|Causative agent (attribute)|



Scg expression
[agent] << 105590001|Substance (substance)| OR << 373873005|Pharmaceutical / biologic product (product)| OR << 410607006 |Organism (organism)|


0..1


Scg expression
363698007 |Finding site (attribute)|



Scg expression
< 123037004 |Body structure (body structure)|


0..1


Scg expression
370135005 |Pathological process (attribute)|



Scg expression
< 308489006 |Pathological process (qualifier value)|


0..1


Scg expression
116676008 |Associated morphology (attribute)|



Scg expression
< 
49755003 |
Morphologically abnormal structure (morphologic abnormality)|


Definition status:  


Scg expression
900000000000073002|Defined (core metadata concept)|


Applies to

Poisoning caused by substance or , product, excluding concepts of types: "Poisoning caused by organism", "Food poisoning","or organism excluding "Overdose", and "Intoxication" (which will have their own templates):


Scg expression
(((<< 789500875478009 |Poisoning caused by drug AND/OR medicinal substance (disorder)|) : [0..0] 42752001 |Due to (attribute)| = 781249001 |Consumption of contaminated food (event)| AND [0..0] 42752001 |Due to (attribute)| = << 418715001 |Exposure to potentially harmful entity (event)| AND [0..0] 246075003 |Causative agentMINUS (<< 1149322001 |Intoxication (disorder)| OR << 1149222004 |Overdose (disorder)| )

Template Language

Scg expression
75478009 |Poisoning (disorder)|: 
[[~0..1]] {[[~0..1]] 263502005 |Clinical course (attribute)| = <<[[ 410607006+id |Organism (organism)| )< OR (( << 441952005 |Poisoning caused by chemical substance (disorder288524001 |Courses (qualifier value)| ) : [0..0 @course]]}, 
[[~0..1]] {[[~0..1]] 42752001 |Due to (attribute)| = 781249001 |Consumption of contaminated food (event)| AND [0..0] 42752001 |Due to (attribute)| = << 418715001 |Exposure to potentially harmful entity (event)| AND [0..0[[ +id ( < 272379006 |Event (event)| ) @dueto ]]}, 
[[~0..2 @rolegroup]] { 
[[~1..1]] 246075003 |Causative agent (attribute)| = [[+id (( << 410607006105590001 |OrganismSubstance (organismsubstance)| ))OR MINUS (<< 1149322001373873005 |IntoxicationPharmaceutical / biologic product (disorderproduct)|) OR << 1149222004410607006 |OverdoseOrganism (disorderorganism)|)

Template Language

Scg expression
75478009 |Poisoning (disorder)|: 
[[~0..1 @causative]], {
[[~0..1]] 263502005363698007 |ClinicalFinding coursesite (attribute)| = [[ +id ( <<< 288524001123037004 |CoursesBody structure (qualifierbody valuestructure)| ) @course]]}, 
[[~0..1]] {[[~0..1]] 42752001 |Due to370135005 |Pathological process (attribute)| = [[+id ( <<  1148742001308489006 |IntentionalPathological eventprocess (eventqualifier value)| OR << 418019003 |Accidental event (event)|) @dueto ]]}, 
[[~0..*]] {[[~0..1]] 246075003116676008 |CausativeAssociated agentmorphology (attribute)| = [[+id ( <<< 10559000149755003 |SubstanceMorphologically abnormal structure (substancemorphologic abnormality)| OR < 373873005 |Pharmaceutical / biologic product (product)|) @causative]]}) ]]}

Note:

  • Pathological process is added to include content under food poisoning.
  • Addition of other attributes such as "246454002 |Occurrence (attribute)|, 363714003 |Interprets (attribute)|, and 363713009 |Has interpretation (attribute)| was considered. However, they were not added due to the very low number of concepts defined by them. Same consideration was applied to expanding the range for 42752001 |Due to (attribute)| to include 71388002 |Procedure (procedure)|, 
     and/or 64572001 |Disease (disorder)| i.e. they were not added as valid values for due to attribute because only a very small number of concepts are defined by them.

Link to the misaligned concept report

https://docs.google.com/spreadsheets/u/0/d/1G-cOv78CFHDprzBYWvb8b2WRCu-PsNxp-0vlzG716nQ/edit

Rules for generating descriptions:

  1. Apply General rules for generating descriptions for templates
  2. Remove the word 'event' and semantic tag from the value of |Due to|

Jira tickets

Jira
serverIHTSDO JIRA
serverIdb202d822-d767-33be-b234-fec5accd5d8c
keyINFRA-12455

EDITORIAL GUIDELINES for Causative agent (attribute):

Disposition

Hierarchy

Concept type

Allowed

Exception

Examples and Notes

SubstanceBaseyesnone

Poisoning concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.

Examples to be added:

  • 13503000 |Poisoning caused by naloxone (disorder)|
  • 30138004 |Poisoning caused by ether (disorder)|

Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the Substance hierarchy.

SubstanceModificationnoyesException and examples to be added

Poisoning concepts representing a substance modification should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Concepts representing substance modifications are exceptions and may be included if the poisoning profile is significantly different from the substance base.

Exception examples:

  • Salt forms (e.g. 273948005 |Chloral hydrate (substance)|, 396063006 |Fluphenazine decanoate (substance)|)

Examples:

  • 62942003 |Tetraethyl pyrophosphate poisoning (disorder)|
SubstanceStructure grouperyesnone

Poisoning concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.

Examples:

  • 1153528004 |Poisoning caused by substance with ether structure (disorder)|

Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the Substance hierarchy.

SubstanceDisposition grouperyesnone

Poisoning concepts representing a disposition grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.

Examples:

  • 9291000 |Poisoning caused by monoamine oxidase inhibitor (disorder)|

Classification results are expected to be addedreflect that the adverse reaction concepts are descendants of the appropriate disposition grouper based on the modeling of the 726542003 |Has disposition (attribute)| attribute in the substance hierarchy.

SubstanceRole groupernonone

Poisoning concepts representing a Role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.

Example:

  • 241748001 |Poisoning caused by analgesic drug (disorder)|

Classification results are expected to reflect that the adverse reaction concepts are descendants of the appropriate disposition grouper based on the modeling of the 726542003 |Has disposition (attribute)| attribute in the substance hierarchy.

ProductStructure Product groupernonone

No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product-containing concepts can be used for modeling in this subhierarchy.

SubstanceRole groupernononeSubstance role groupers to be replaced by product role groupers
ProductRole grouperyesnone

 Examples to be added - pending

SubstanceStructure grouperyesnone

 Examples to be added


ProductDisposition ProductStructure groupernononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product-containing concepts can be used for modeling in this subhierarchy.
ProductRole grouperyesnone

Examples to be added - pending implementation of roles and products as causative agents

ProductMedicinal product-containingyesnone

examples Examples to be added - pendingpending implementation of roles and products as causative agents

ProductMedicinal product-onlynononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product-containing concepts can be used for modeling in this subhierarchy.
ProductMedicinal product form-containingnononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy.
ProductMedicinal product form-onlynononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy.
ProductClinical drugnononeNo use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy.

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