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Page properties |
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Status | In progressReady for implementation |
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Version | 1.0.1 |
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Descriptions:
Term | description type | Language/acceptability | LangaugeLanguage/acceptability | Case significance |
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[Accidental/Intentional] [course] [substance or product] overdose overdose (disorder) | FSN | us:P | gb:P | ci |
[Accidental/Intentional] [course] [substance or product] overdose overdose | SYN | us:P | gb:P | ci |
Concept model:
Attribute Group Cardinality | Attribute |
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cardinality cardinality role groupGroup Cardinality | Attribute | Value |
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0..0 | 1..1 |
0..0 75478009 |Poisoning |
Scg expression |
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1149222004 |Overdose (disorder)| |
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0..1 |
| 0..1 | |
|Clinical course (attribute)| |
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< |
Scg expression |
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< 288524001 |
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288524001 |Courses (qualifier value)| |
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0..1 |
| 0..1 | |
<< |
Scg expression |
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<< 1148742001 |
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1148742001 |Intentional event (event)| |
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OR << 418019003 OR << 418019003 |Accidental event (event)| |
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0.. |
* |Causative agent (attribute)| |
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<< OR << 373873005 OR << 373873005|Pharmaceutical / biologic product (product)| |
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Definition status:
...
Concept model:
...
...
...
900000000000073002|Defined (core metadata concept)| |
Applies to:
Scg expression |
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<< 1149222004 |Overdose (disorder)| |
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Template Language
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...
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Scg expression |
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[agent] << 105590001 |Substance (substance)| OR << 373873005 |Pharmaceutical / biologic product (product)| |
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:
[[~0..1]] {[[~0..1]] 263502005 |Clinical course (attribute)| = [[ +id ( < 288524001 |Courses (qualifier value)|) @course]]},
[[~0..1]] {[[~0..1]] 42752001 |Due to (attribute)| |
...
= [[+id ( << 1148742001 |Intentional event (event)| OR << 418019003 |Accidental event (event)| |
...
...
...
...
...
...
Scg expression |
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< 288524001 |Courses (qualifier value)| |
= [[+id ( < 105590001 |Substance (substance)| OR < 373873005 |Pharmaceutical / biologic product (product)|) @causative]]} |
Link to the misaligned concept report
Overdose misaligned concept report 2021-Dec-14
Rules for generating descriptions:
- Apply General rules for generating descriptions for templates
Definition status:
Scg expression |
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900000000000073002|Defined (core metadata concept)| |
Template Language
Applies to:
...
Editorial guidelines for selection of Causative agent attribute value:
The following editorial guidelines apply to concepts in the International Release; editorial guidelines for concepts in national extensions may vary.
Causative agent Concept type | Allowed | Exception | Examples and Notes (Note: Examples are existing concepts and may not reflect the terming patterns described in the template.) |
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Substance |
baseOverdose concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.Substance modification | no, unless documented as exception | Overdose concepts representing a substance modification should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. n/a | Example: - 295184007 |Morphine overdose (disorder)|
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Expected classification:
- Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the Substance hierarchy.
Substance | Modification | yes | yes |
Concepts representing substance modifications are exceptions and may be included if the overdose profile is significantly different from the substance base. Exception examples: |
Chemical element with multiple modifications (e.g. 422232005 |Calcium lactate gluconate (substance)|)- Liposome or lipid complex substances (e.g. 412088006 |Amphotericin B liposome (substance)|, 426490000 |Vincristine liposome (substance)|)
- Pegylated substance (e.g. 385544005 |Pegfilgrastim (substance)|, 770965008 |Pegvaliase (substance)|)
- Salt forms (e.g. 273948005 |Chloral hydrate (substance)|
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)Example:
296213007 - , 396063006 |Fluphenazine decanoate
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overdose (disorder)|296217008 |Fluphenazine enanthate overdose (disorder)|Expected classification:
- Classification results are expected to reflect that the concept modeled with the modified substance is a descendant of the concept modeled with the base substance (if such a concept exists.
Multiple substance | yes | Adverse reaction concepts representing multiple substances should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|; preferentially modeling with the base rather than a modification unless the adverse reaction profile is significantly different from the substance base.292984002 |Ampicillin and cloxacillin adverse reaction 292989007 |Ticarcillin and clavulanic acid adverse reaction - 296136008 |Chloral hydrate overdose (disorder)|
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292987009 |Piperacillin and tazobactam adverse reaction (disorder)|- 296213007 |Fluphenazine decanoate overdose (disorder)|
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Expected classification (Agreed 21-Jan-2020):Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the hierarchy.Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the | Disposition grouper | yes | n/a | Overdose concepts representing a disposition grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example: - 297053006 |Overdose of angiotensin-converting-enzyme inhibitors (disorder)|
- 296515004 |Opiate antagonist overdose (disorder)|
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Expected classification results:
hierarchy. | Role grouper | yes | n/a | Overdose concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. |
Note that role Role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release. Example: - 297006008 |Diuretic overdose (disorder)|
- 295217003 |Non-steroidal anti-inflammatory overdose (disorder)|
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Expected classification results (to be revised when concepts are remodeled using Medicinal product ):Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the hierarchy. | Structure grouper | yes | n/a | Overdose concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example: |
218638005 |Adverse reaction caused by hydantoin derivative - 295188005 |Pethidine analog overdose (disorder)|
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419885006 |Beta lactam adverse reaction - 1155996000 |Phenothiazine and/or phenothiazine derivative overdose (disorder)|
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Expected classification (Agreed 21-Jan-2020):
- Classification results are expected to be consistent with the Substance hierarchy and with other existing concepts in the subhierarchy.
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Product | Structure grouper | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Disposition grouper | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Role grouper | no | n/a | Overdose concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release. |
Product | Medicinal product-containing | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Medicinal product-only | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Medicinal product form-containing | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Medicinal product form-only | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Clinical drug | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Descendant of 373873005 |Pharmaceutical / biologic product (product)| | no, unless documented as exception | Exceptions: None identified The following types of groupers are out of scope; existing concepts have been inactivated or will be addressed in future release:
- Groupers based on more than one role (e.g. 292722006 |Chelating agents and antidotes adverse reaction (disorder)|)
- Groupers based on body system or intended site or route of administration (e.g. 292548001 |Drug groups primarily affecting respiratory system adverse reaction (disorder)|) or 417895009 |Topical agent adverse reaction (disorder)|)
- Groupers based on disposition, role, or structure combined with an individual substance (e.g. 287177000 |Sulfonamide/trimethoprim reaction (disorder)| or 292513008 |Methyldopa and diuretic adverse reaction (disorder)|)
- Groupers based on "combined" or "compound" substances (e.g. 292983008 |Combined penicillin preparation adverse reaction (disorder)| or 293358005 |Compound iron preparations adverse reaction (disorder)|)
- Groupers based on disposition or structure combined with intended site or route of administration (e.g. 433494006 |Adverse effect of oral diphosphonate (disorder)|)Groupers based on disposition combined with role (e.g. 292265006 |Dopaminergic drug used in parkinsonism adverse reaction (disorder)|)
Rules for description generation:
- For the FSN, align terming and case sensitivity with the FSN for the concept that is selected as the attribute value, excluding the semantic tag.
- For the PT, align terming and case sensitivity with the US and GB PT for the concept that is selected as the attribute value.
- In cases where neither the US or GB PT matches the FSN, excluding the semantic tag, a synonym corresponding to the FSN is required unless explicitly identified as an exception.Additional synonyms "[agent] adverse reaction" should be added. Other synonyms are not allowed unless explicitly identified as an exception.
JIRA ticket for implementation:
Jira |
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server | IHTSDO JIRA |
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serverId | b202d822-d767-33be-b234-fec5accd5d8c |
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key | INFRA-8098 |
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