Page properties |
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Status | Ready for implementation |
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Version | 1.0 |
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Descriptions:
Term | description type | Language/acceptability | Language/acceptability | Case significance |
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Product containing precisely [substance][number][SI unit Unit of massmeasure ]/[1 ] each [dose form] (clinical drug) | FSN | us:P | gb:P | ci |
[substance] [SI unit of massnumber] [Unit of measure ] [dose form] | SYN | us:P | gb:P | ci |
Concept model:
Role group cardinality | Attribute cardinality | Attribute in role group cardinality | Attribute | Value | role group number | role group cardinality
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0..0 | 1..* |
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Scg expression |
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116680003|Is a (attribute)| |
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Scg expression |
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3763158003763158003 |Medicinal product (product)| |
| 0 | N/A |
0..0 | 1..1 |
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Scg expression |
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411116001 |Has manufactured dose form (attribute)| |
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Scg expression |
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<736542009 |Pharmaceutical dose form (dose form)| |
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0 | 1.. | 10 | 1..1 |
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Scg expression |
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763032000 |Has unit of presentation (attribute)| |
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Scg expression |
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<732935002 | Unit of presentation (unit of presentation) | |
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0 | 1.. | 10 | 1..1 |
| | 7669520061142139005 |Count of base of active ingredient (attribute)| |
| |
<260299005 |Number (qualifier value)| |
0 | 1..1 | 0..0 | 0..1 |
| | 7669540071142141006 |Count of base and modification pair (attribute)| |
| | 0 |
<260299005 |Number (qualifier value)| |
| 0.. | 10 | 0..1 |
| | 7669530011142140007 |Count of active ingredient (attribute)| |
| |
<260299005 |Number (qualifier value)| |
0 | 0..1 | 1..* |
| 1..1 |
Scg expression |
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762949000 |Has precise active ingredient (attribute)| |
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Scg expression |
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<105590001 |Substance (substance)| |
| 1 |
| 1..1 | 1..1 |
Scg expression |
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732943007|Has basis of strength substance (attribute)| |
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Scg expression |
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<105590001 |Substance (substance)| |
| 1 |
| 1..1 | | 7329440011142135004 |Has presentation strength numerator value (attribute)| |
| |
| 1 |
<260299005|Number (qualifier value)| |
1 | 1..1 |
Scg expression |
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732945000|Has presentation strength numerator unit (attribute)| |
| | <258681007 | International System | Units unit of mass measure (qualifier value)| |
| 1 |
| 1..1 | | 7329460041142136003 |Has presentation strength denominator value (attribute)| |
| 1 |
38112003|1 (qualifier value)| |
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| 1..1 |
Scg expression |
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732947008|Has presentation strength denominator unit (attribute)| |
| | 732935002 | presentation | unit | of presentation | 1 | |
Definition status:
Scg expression |
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900000000000073002|Defined (core metadata concept)| |
Rules for description generation:
Applies To:
Scg expression |
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<< 763158003 |Medicinal product (product)| : 411116001 |Has manufactured dose form (attribute)| = < 736542009 |Pharmaceutical dose form (dose form)|, 763032000 |Has unit of presentation (attribute)| = < 732935002 |Unit of presentation (unit of presentation)|, 1142139005 |Count of base of active ingredient (attribute)| = * |
Template Language
Scg expression |
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763158003 |Medicinal product (product)| :
[[~1..1]] 411116001 |Has manufactured dose form (attribute)| = [[ +id( < 736542009 |Pharmaceutical dose form (dose form)|) @form]],
[[~1..1]] 763032000 |Has unit of presentation (attribute)| = [[ +id( < 732935002 |Unit of presentation (unit of presentation)|) @presentation]],
[[~1..1]] 1142139005 |Count of base of active ingredient (attribute)| = [[ int(>#0..) @baseCount]],
[[~0..1]] 1142141006 |Count of base and modification pair (attribute)| = [[ int(>#0..) @baseModCount]],
[[~0..1]] 1142140007 |Count of active ingredient (attribute)| = [[ int(>#0..) @ingredCount]],
[[~1..*]] {
[[~1..1]] 762949000 |Has precise active ingredient (attribute)| = [[ +id( < 105590001 |Substance (substance)|) @ingred]],
[[~1..1]] 732943007 |Has basis of strength substance (attribute)| = [[ +id( < 105590001 |Substance (substance)|) @boss]],
[[~1..1]] 1142135004 |Has presentation strength numerator value (attribute)| = [[ dec(>#0..) @presStrenNumVal]],
[[~1..1]] 732945000 |Has presentation strength numerator unit (attribute)| = [[ +id( < 767524001 |Unit of measure (qualifier value)|) @presStrenNumUnit]],
[[~1..1]] 1142136003 |Has presentation strength denominator value (attribute)| = #1,
[[~1..1]] 732947008 |Has presentation strength denominator unit (attribute)| = [[ +id( < 767524001 |Unit of measure (qualifier value)|) @presStrenDenomUnit]]} |
Rules for description generation:
- Apply General rules for generating descriptions for templates
For multiple ingredients, the BoSS substance
- Apply General rules for generating descriptions for templates
- Exceptions:Concepts with product strength that is "not equal to" (e.g. with product strength expressed as a range, greater than, or less than) will have definition status 900000000000074008| Primitive (core metadata concept) and will have the appropriate Medicinal Product Form-only (MPF-only) concept as a stated parent.
- For multiple ingredients, the
ingredients in each description need to be in alphabetical
order e.g. Codeine and paracetamol for FSN but Acetaminophen and codeine (for US PT).order
For multiple ingredients, for FSN add 'and [substance][number][Unit of measure ]' after the first [substance][number][Unit of measure ] for each |Has basis of strength substance (attribute)| Example: 413382007 |Product containing precisely abacavir 600 milligram and lamivudine 300 milligram/1 each conventional release oral tablet (clinical drug)|.
For multiple ingredients PT - add ' [substance][number][Unit of measure ] and' at the beginning of the PT Example; Abacavir 600 mg and lamivudine 300 mg oral tablet
- PT uses Preferred Terms in values; Example where BoSS = Precise active ingredient:<BoSS substance PT> <Presentation strength numerator value PT> <Presentation strength numerator unit PT> <Manufactured dose form value PT>
Example; Abacavir 300 mg oral tablet
FSN Exceptions: a. If substance value for Precise active ingredient <> BoSS add (as [substance]) to text string as illustrated below. The substance value in parentheses uses the substance value for the Precise active ingredient (PAA) and not the BoSS, which is the first substance value in the description:
Product containing precisely [BoSS substance] (as [PAA
If BOSS differs from precise active ingredient BoSS <> Precise active ingredient:
FSN Product containing precisely [substance](as[ substance]) [number] [SI unit Unit of massmeasure ]/[1 ] each [dose form] (clinical drug) e.g
Example:
Product containing precisely doxazosin (as doxazosin mesilate) 8 4 milligram/1 each prolonged-conventional release oral tablet (clinical drug)
b. Where Manufactured dose form value is NOT < 421378002 |Basic dose form with solid state of matter (basic dose form)PT [substance] | then include a value for Presentation strength denominator unit and remove “each” from text string:
Product containing precisely [substance][number][Unit of measure ]/1 [Unit of presentation] [dose form] (clinical drug)
Examples:
- Product containing precisely aztreonam 500 milligram/1 vial powder for conventional release solution for injection (clinical drug)
- Product containing precisely budesonide 200 microgram/1 actuation conventional release powder for inhalation (clinical drug)
- PT Exceptions:
a. Where BoSS <> Precise active ingredient:
The substance value in parentheses uses the substance value for the Precise active ingredient and not the BoSS, which is the first substance value in the description:
[substance] (as [substance]) [SI unit of mass PT[number][Unit of measure ] [dose form] e.g. US with GB language Acceptability: Doxazosin
Example:Showing also US and GB dialect spelling variations in PT:
US PT: Doxazosin (as doxazosin mesylate)
...
4 mg
...
oral tablet
...
(GB Acceptable)
GB PT: Doxazosin (as doxazosin mesilate)
...
4 mg
...
oral tablet
...
(US Acceptable
...
)
b. Where the concept Has unit of presentation (unit of presentation) has value = Actuation (unit of presentation) then for FSN show value as '/1 actuation' Example:
770274000 |Product containing precisely beclometasone dipropionate 200 microgram/1 actuation pressurized conventional release solution for inhalation (clinical drug)
...
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Example PT: Aclidinium bromide 375 microgram/actuation powder for inhalation
7. The following units of measure should not be abbreviated in descriptions; they should always be spelled out: international unit, microgram, million unit, nanogram, picogram, unit
JIRA tickets:
Jira |
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server | IHTSDO JIRA |
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columns | key,summary,type,created,updated,due,assignee,reporter,priority,status,resolution |
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serverId | b202d822-d767-33be-b234-fec5accd5d8c |
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key | DRUGS-276 |
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Jira |
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server | IHTSDO JIRA |
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columns | key,summary,type,created,updated,due,assignee,reporter,priority,status,resolution |
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serverId | b202d822-d767-33be-b234-fec5accd5d8c |
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key | DRUGS-645 |
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Jira |
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server | IHTSDO JIRA |
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serverId | b202d822-d767-33be-b234-fec5accd5d8c |
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key | INFRA-3212 |
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Jira |
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server | IHTSDO JIRA |
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serverId | b202d822-d767-33be-b234-fec5accd5d8c |
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key | INFRA-12544 |
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|
Jira |
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server | IHTSDO JIRA |
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serverId | b202d822-d767-33be-b234-fec5accd5d8c |
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key | INFRA-12577 |
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