Page properties |
---|
Status | In progressReady for implementation |
---|
Version | 1.0.1 |
---|
|
Descriptions:
Term | description type | Language/acceptability | LangaugeLanguage/acceptability | Case significance |
---|
Overdose [Accidental/Intentional] [course] [substance or product] overdose (disorder) | FSN | us:P | gb:P | ci |
Overdose [Accidental/Intentional] [course] [substance or product] overdose | SYN | us:P | gb:P | ci |
Concept model:
Attribute Group Cardinality | Attribute Cardinality |
---|
Value | Role group number | Role group cardinalityn/a | Attribute in Group Cardinality | Attribute | Value |
---|
0..0 | 1..1 |
|
Scg expression |
---|
116680003 |Is a (attribute)| |
|
Scg expression |
---|
1149222004 |Overdose (disorder)| |
|
0 |
246075003Causativeagent[agent] << 105590001 |Substance (substance)| OR << 373873005 |Pharmaceutical / biologic product (product)| |
0< 288524001 |Courses (qualifier value)| |
|
0..1 |
| 0..1 |
Scg expression |
---|
42752001 |Due to (attribute)| |
| |
< 272379006 |Event<< 1148742001 |Intentional event (event)| OR << 418019003 |Accidental event (event)| |
|
0 |
0263502005 Clinicalcourse< 288524001 |Courses (qualifier value)| |
0 | 0..1 | [agent] << 105590001|Substance (substance)| OR << 373873005|Pharmaceutical / biologic product (product)| |
|
Definition status:
Scg expression |
---|
900000000000073002|Defined (core metadata concept)| |
...
Applies to:
Scg expression |
---|
<< 1149222004 |Overdose (disorder)| |
Template Language
Scg expression |
---|
1149222004 |Overdose (disorder)|:
[[~0..1]] {[[~0..1]] 263502005 |Clinical course (attribute)| = [[ +id ( < 288524001 |Courses (qualifier value)|) @course]]},
[[~0..1]] {[[~0..1]] 42752001 |Due to (attribute)| = [[+id ( << 1148742001 |Intentional event (event)| OR << 418019003 |Accidental event (event)|) @dueto ]]},
[[~0..1]] {[[~0..1]] 246075003 |Causative agent (attribute)| = [[+id ( < 105590001 |Substance (substance)| OR < 373873005 |Pharmaceutical / biologic product (product)|) @causative]]} |
Link to the misaligned concept report
Overdose misaligned concept report 2021-Dec-14
Rules for generating descriptions:
- Apply General rules for generating descriptions for templates
Editorial guidelines for selection of Causative agent attribute value:
The following editorial guidelines apply to concepts in the International Release; editorial guidelines for concepts in national extensions may vary.
Causative agent type | Allowed | Exception | Examples and Notes (Note: Examples are existing concepts and may not reflect the terming patterns described in the template.) |
---|
Substance |
baseOverdose concepts representing a substance base should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|.Substance modification | no, unless documented as exception | Overdose concepts representing a substance modification should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. n/a | Example: - 295184007 |Morphine overdose (disorder)|
|
Expected classification:
- Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the Substance hierarchy.
Substance | Modification | yes | yes |
Concepts representing substance modifications are exceptions and may be included if the overdose profile is significantly different from the substance base. Exception examples: |
Chemical element with multiple modifications (e.g. 422232005 |Calcium lactate gluconate (substance)|)- Liposome or lipid complex substances (e.g. 412088006 |Amphotericin B liposome (substance)|, 426490000 |Vincristine liposome (substance)|)
- Pegylated substance (e.g. 385544005 |Pegfilgrastim (substance)|, 770965008 |Pegvaliase (substance)|)
- Salt forms (e.g.
|
412432007 Metoprolol succinate - Chloral hydrate (substance)|,
|
72770009 Metoprolol tartrate - Fluphenazine decanoate (substance)|)
Example: |
296213007 Fluphenazine decanoate - Chloral hydrate overdose (disorder)|
|
296217008 enanthate - decanoate overdose (disorder)|
|
Expected classification:- Classification results are expected to reflect that the concept modeled with the modified substance is a descendant of the concept modeled with the base substance (if such a concept exists.
Multiple substance | yes | Adverse reaction concepts representing multiple substances should be modeled using a Causative agent that is a descendant of 105590001 | (substance)|; preferentially modeling with the base rather than a modification unless the adverse reaction profile is significantly different from the substance base.Example:
- 292984002 |Ampicillin and cloxacillin adverse reaction (disorder)|
- 292987009 |Piperacillin and tazobactam adverse reaction (disorder)|
- 292989007 |Ticarcillin and clavulanic acid adverse reaction (disorder)|
Expected classification (Agreed 21-Jan-2020):- Classification results are expected to be consistent with the modeling of the concept selected as the Causative agent in the Substance hierarchy.
Classification results are expected to reflect that the overdose concepts are descendants of the appropriate disposition grouper based on the modeling of the 726542003 |Has disposition (attribute)| attribute in the substance hierarchy (e.g. 296516003 |Naloxone overdose (disorder)| has inferred parent 296515004 |Opiate antagonist overdose (disorder)|).Disposition grouper | yes | n/a | Overdose concepts representing a disposition grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example: - 297053006 |Overdose of angiotensin-converting-enzyme inhibitors (disorder)|
- 296515004 |Opiate antagonist overdose (disorder)|
|
Expected classification results:
Adverse reaction n/a | Overdose concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. |
Note that role Role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release. Example: |
430136001 |Adverse reaction caused by antiparkinsonism drug - 297006008 |Diuretic overdose (disorder)|
|
292040004 |Analgesic adverse reaction - 295217003 |Non-steroidal anti-inflammatory overdose (disorder)|
|
Expected classification results (Agreed 21-Jan-2020):
Classification results are expected to reflect that the adverse reaction concepts are descendants of the appropriate disposition grouper based on the modeling of the 726542003 |Has disposition (attribute)| attribute in the substance hierarchy (e.g. 292113001 |Lansoprazole adverse reaction (disorder)| has inferred parent 292111004 |Proton pump inhibitor adverse reaction (disorder)|).Classification results are expected to be consistent with the modeling in the Substance hierarchy for concepts modeled with an attribute value from the Substance hierarchy. |
Substance | Structure grouper | yes | n/a | Overdose concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example: - 295188005 |Pethidine analog overdose (disorder)|
- 1155996000 |Phenothiazine and/or phenothiazine derivative overdose (disorder)|
|
Product | Structure grouper | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Disposition grouper | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Role grouper | no | n/a | Overdose concepts representing a role |
Structure grouper | yes | Adverse reaction concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. |
Example:
- 218638005 |Adverse reaction caused by hydantoin derivative (disorder)|
- 419885006 |Beta lactam adverse reaction (disorder)|
Expected classification (Agreed 21-Jan-2020):
- Classification results are expected to be consistent with the modeling in the Substance hierarchy and with other existing concepts in the subhierarchy.
Role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in a future release. |
Product | Medicinal product-containing | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Medicinal product-only | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Medicinal product form-containing | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Medicinal product form-only | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Product | Clinical drug | no | n/a | No use case has been identified for use of this concept type for modeling in this subhierarchy. |
Descendant of 373873005 |Pharmaceutical / biologic product (product)| | no, unless documented as exception | Exceptions: None identified The following types of groupers are out of scope; existing concepts have been inactivated or will be addressed in future release:
- Groupers based on more than one role (e.g. 292722006 |Chelating agents and antidotes adverse reaction (disorder)|)
- Groupers based on body system or intended site or route of administration (e.g. 292548001 |Drug groups primarily affecting respiratory system adverse reaction (disorder)|) or 417895009 |Topical agent adverse reaction (disorder)|)
- Groupers based on disposition, role, or structure combined with an individual substance (e.g. 287177000 |Sulfonamide/trimethoprim reaction (disorder)| or 292513008 |Methyldopa and diuretic adverse reaction (disorder)|)
- Groupers based on "combined" or "compound" substances (e.g. 292983008 |Combined penicillin preparation adverse reaction (disorder)| or 293358005 |Compound iron preparations adverse reaction (disorder)|)
- Groupers based on disposition or structure combined with intended site or route of administration (e.g. 433494006 |Adverse effect of oral diphosphonate (disorder)|)
- Groupers based on disposition combined with role (e.g. 292265006 |Dopaminergic drug used in parkinsonism adverse reaction (disorder)|)
Rules for description generation:
- For the FSN, align terming and case sensitivity with the FSN for the concept that is selected as the attribute value, excluding the semantic tag.
- For the PT, align terming and case sensitivity with the US and GB PT for the concept that is selected as the attribute value.
- In cases where neither the US or GB PT matches the FSN, excluding the semantic tag, a synonym corresponding to the FSN is required unless explicitly identified as an exception.Additional synonyms "[agent] adverse reaction" should be added. Other synonyms are not allowed unless explicitly identified as an exception.
JIRA ticket for implementation:
Jira |
---|
server | IHTSDO JIRA |
---|
serverId | b202d822-d767-33be-b234-fec5accd5d8c |
---|
key | INFRA-8098 |
---|
|