Page History

Descriptions:

Concept model:

116680003|Is a (attribute)|

3763158003|Medicinal product (product)

766952006411116001 |CountHas ofmanufactured base of active ingredientdose form (attribute)|

<260299005<736542009 |NumberPharmaceutical dose form (qualifierdose valueform)|

763032000766952006 |HasCount of unitbase of active presentationingredient (attribute)|

<732935002<260299005 | Unit of presentationNumber (unitqualifier of presentationvalue) |

411116001763032000 |Has manufacturedunit doseof formpresentation (attribute)|

<736542009<732935002 |Pharmaceutical Unit doseof formpresentation (doseunit of formpresentation)| 

762949000 |Has precise active ingredient (attribute)|

<105590001 |Substance (substance)|

732943007|Has basis of strength substance (attribute)|

<105590001 |Substance (substance)|

732944001|Has presentation strength numerator value (attribute)|

<260299005|Number (qualifier value)|

732945000|Has presentation strength numerator unit (attribute)|

<258681007 |International System of Units unit of mass (qualifier value)|

732946004|Has presentation strength denominator value (attribute)|

38112003|1 (qualifier value)|

732947008|Has presentation strength denominator unit (attribute)|

732935002 |Unit of presentation (unit of presentation)|

Definition status:  

900000000000073002|Defined (core metadata concept)|

Rules for description generation:

1. Apply General rules for generating descriptions for templates
2. Exceptions:Concepts with product strength that is "not equal to" (e.g. with product strength expressed as a range, greater than, or less than) will have definition status 900000000000074008| Primitive (core metadata concept) 

3. For multiple ingredients, the ingredients in each description need to be in alphabetical order e.g. Codeine and paracetamol for FSN but Acetaminophen and codeine (for US PT).

4. Remove the semantic tags, (substance) (unit of presentation) (dose form) and (qualifier value) 
5. For clinical drug PT SI Unit of mass uses the PT which is an abbreviation e.g. mg   
6. A Preferred Term (PT) for both US and GB dialect as per the substance concept terming must be added where there are US and GB spelling variations (language acceptability P/A) 

7. Align case sensitivity with substance term  

8. If BOSS differs from precise active ingredient BoSS <> Precise active ingredient:

   FSN Product containing precisely [substance](as[substance]) [number][SI unit of mass]/[1] each [dose form] (clinical drug) e.g Product containing precisely doxazosin (as doxazosin mesilate) 8 milligram/1 each prolonged-release oral tablet (clinical drug)

   PT [substance] (as[substance]) [SI unit of mass PT] [dose form] e.g. US with GB language Acceptability:

   Doxazosin (as doxazosin mesylate) 8 mg prolonged-release oral tablet	Preferred
   Doxazosin (as doxazosin mesilate) 8 mg prolonged-release oral tablet	Acceptable

9. Exceptions:use Use of 'actuation' - 
   Product containing precisely budesonide 200 microgram/actuation conventional release powder for inhalation (clinical drug)
10. Use of 'vial powder':•Product containing precisely aztreonam 500 milligram/1 vial powder for conventional release solution for injection (clinical drug)JIRA ticket for implementation: