Examples: bulk powders and granules, bulk liquids, semi-solids

These presentations are not particularly bound by their container in any way that is meaningful in terms of their use or administration; the Manufactured Item is a continuous presentation and almost all are used in individually calculated and variable amounts.

For example,

A unit of presentation is not usually given for these products. The pack size (not relevant for SNOMED international model) is given as the Manufactured Item quantity.
Strength is expressed as a concentration and as such the presentation strength and the concentration are exactly the same.

Example 1: A 30g tube of hydrocortisone 1% cutaneous cream w/w in an outer box

Manufactured dose formCutaneous cream
Unit of presentationNOT VALUEDThere is nothing that really "bounds" the dose form that delivers the medication "per dose"
[Pack size]30 g in the tube,1 tube in the box
Precise active ingredienthydrocortisone
Basis of strength substancehydrocortisone
Presentation strength (logical)300 mg per 30 gNot a clinically safe or recognisable expression of strength
Presentation strength

Concentration strength10 mg per 1 gSynonym: 1.0 % w/w


Example 2: A bottle of 5 mL of chloramphenicol eye drops 0.5% w/v in an outer box



Manufactured dose formEye drops, solution
Unit of presentationNOT VALUEDThere is nothing that really "bounds" the dose form that delivers the medication "per dose"
[Pack size]5 ml in the dropper bottle,1 bottle in the box
Precise active ingredientchloramphenicol
Basis of strength substancechloramphenicol
Presentation strength (logical)25 mg per 5 mLNot a clinically safe or recognisable expression of strength
Presentation strength

Concentration strength5 mg per 1 mLSynonym: 0.5 % w/v


Example 3: A pack of 500g of sterculia 62% w/w granules (EDQM –"granules" = "oral granules")

Manufactured dose formOral granules
Unit of presentationNOT VALUEDThere is nothing that really "bounds" the dose form that delivers the medication "per dose"
[Pack size]500 g in the box
Precise active ingredientsterculia
Basis of strength substancesterculia
Presentation strength (logical)310 g per 500 gNot a clinically safe or recognisable expression of strength
Presentation strength

Concentration strength620 mg per 1 gSynonym: 62 % w/w



Example 4: A bottle of 60 mL of digoxin oral solution 50mcg/mL in an outer box (which has an oral syringe in it)

Manufactured dose formOral solution
Unit of presentationNOT VALUEDThere is nothing that really "bounds" the dose form that delivers the medication "per dose"
[Pack size]60 ml in the bottle,1 bottle in the box
Precise active ingredientdigoxin
Basis of strength substancedigoxin
Presentation strength (logical)3 mg per 60 mLNot a clinically safe or recognisable expression of strength
Presentation strength

Concentration strength50 mcg per 1 mLSynonym: 0.5 % w/v