Updates on Substances Co-Ordination:

• Step 1: Substances in multiple extensions
• Step 2: Substances in one extension
  • Country self-review/first pass
  • Then, SI will review in scope

Updates on development work in relation to hydration substances.

• SI
• Canada

For Information: WHO recommended flu vaccine antigen substances for 2025/2026 season (Northern Hemisphere) are now available in International Release

Feedback on Canada plans to use the |Physical object| hierarchy (specifically < 398124009 |Drug container (physical object)|) for the range of the |Has container type| relationship

Group feedback sought on 'Drug Therapy' versus 'Administration of Drug' on Discussion Forum

1. National Extension Model Guide: User query on FSNs and PTs for combination 'Packaged Clinical Drug'. How are countries approaching this?

• Hydration Subsumption
• Less Granular Clinical Drug
• Elemental Substances (Matt, AUS)
• Substances Co-ordination
  • Step 1: Substances in multiple extensions
  • Step 2: Substances in one extension
  • Step 3: Ongoing Substance Co-ordination (capturing at regulator level)
• Medication Stopped v Medication Discontinued (Karen, SI)
• Medicinal Product promotion co-ordination (Oslo group discussion as linked to substances work + ES)
• Value range of a |Has container type| attribute (Linda, CA)
• Top level children of 373873005 |Pharmaceutical / biologic product| hierarchy - are members using/how are members using? (AUS) 
• Routes of Administration - Implementation Considerations (Mia, NZ)
• Group Input on Patch Strength Representation
• Dose Form Intended Site v Route of Administration (BEL)
• Drug extension MRCM attributes (CA, AUS)