Representation of radioactive isotopes

Modeling (stated view)

Parent concept

Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)|

  • Exceptions: none

Most distal appropriate descendant of 33638001 |Isotope (substance)|

  • Exceptions: none
Semantic tag

(substance)

Definition status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

  • Exceptions: none

Attribute:

Is Modification

738774007 | Is modification of

  • Range  <105590001 |Substance (substance)|
  • Cardinality: 0..*
  • Exceptions: none identified
  • One relationship to be created to represent each modified component of the substance

Attribute:

Has disposition

  • Range:  <726711005 |Disposition (disposition) |
  • NOTE: While the allowed range is broader, substance concepts should only use descendants of the concept 726711005 |Disposition (disposition)| as the attribute value.
  • Cardinality: 0..1
  • Exceptions: none identified

Naming Guidelines

Superscripts should not be used in either Fully Specified Name, Preferred Term, or Synonyms.

FSN

Pattern:

  • [name of isotope]-[atomic number] (substance)

Example:

  • Gallium-67 (substance)

Preferred Term

Pattern:

[name of isotope]-[atomic number]

Example:

  • Gallium-67

Synonyms

Pattern:

  • [atomic number]-[chemical symbol]

Example:

  • 67-Ga
    No synonyms should exist using the superscript notation.


Exemplar

The following illustrates the hierarchy view:


The following illustrates the stated and inferred view:

Representation of radioisotope with salt

Modeling (stated view)

Parent concept

Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)|

  • Exceptions: none
Semantic tag

(substance)

Definition status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

  • Exceptions: none

Attribute:

Is modification

738774007 | Is modification of

  • Range  <105590001 |Substance (substance)|
  • Cardinality: 0..*
  • Exceptions: none identified
  • One relationship to be created to represent each modified component of the substance

Attribute:

Has disposition

  • Range:  <726711005 |Disposition (disposition) |
  • NOTE: While the allowed range is broader, substance concepts should only use descendants of the concept 726711005 |Disposition (disposition)| as the attribute value.
  • Cardinality: 0..1
  • Exceptions: none identified

Naming Guidelines

Superscripts should not be used in either Fully Specified Name, Preferred Term, or Synonyms.

Parentheses should be used to delineate the atomic number and chemical symbol from the rest of the terming, this aligns with INN.  

FSN

Pattern:

  • [name of isotope] ([atomic number]-[chemical symbol]) [salt] (substance)

Example:

    • Gallium (67-Ga) citrate (substance)

Preferred Term

Pattern:

[name of isotope] ([atomic number]-[chemical symbol]) [salt]

Example:

  • Gallium (67-Ga) citrate

Synonyms

Pattern:

  • none identified

Exemplar - radioisotope with salt

The following illustrates the stated and inferred view:

Representation of combined radioisotope substances

Modeling (stated view)

Parent concept

Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)| and a second parent identifying the labelled component

  • Exceptions: none
Semantic tag

(substance)

Definition status

900000000000074008|Necessary but not sufficient concept definition status (core metadata concept)|

  • Exceptions: none

Attribute

Is modification

738774007 | Is modification of

  • Range  <105590001 |Substance (substance)|
  • Cardinality: 0..*
  • Exceptions: none identified
  • One relationship to be created to represent each modified component of the substance

Attribute:

Has disposition

  • Range:  <726711005 |Disposition (disposition) |
  • NOTE: While the allowed range is broader, substance concepts should only use descendants of the concept 726711005 |Disposition (disposition)| as the attribute value.
  • Cardinality: 0..1
  • Exceptions: none identified

Naming Guidelines

Superscripts should not be used in either Fully Specified Name, Preferred Term, or Synonyms.

The Fully Specified Name should explicitly state that a component was “labeled” by a radioisotope in the FSN. Do not use “with”, “and”, or “tagged”.  

Omit the word “labeled” from the PT, keep a synonym to match the FSN.  

Exemplar - combined radioisotope substances

The following illustrates both the stated and inferred view: