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    • Concept
      t4989003 |Electrical burn of skin (disorder)|
       has the 
      Concept
      t246075003 |Causative agent (attribute)|
       
      of 
      Concept
      t18213006 |Electricity (physical force)|

Although Pharmaceutical / biologic product (product) and its descendants are considered valid values for Causative agent (attribute) by the MRCM, they are not currently used as values for this attribute in the International Release. The only exception is 787859002 |Vaccine product (medicinal product)| and its descendants, which can be used as valid values for this attribute.

The following guidelines should be considered where the causative agent is a substance:

Concepts representing a clinical finding caused by a base substance (e.g., 836284001 |Pentamethonium (substance)|), a substance structure grouper (e.g. 1149501006 |Substance with ether structure (substance)|), or a substance disposition grouper (e.g. 404642006 |Substance with opioid receptor agonist mechanism of action (substance)|) should be modeled using a causative agent that is a descendant of 105590001 |Substance (substance)|. Classification results are expected to be consistent with the modeling in the Substance hierarchy:

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Tip
titleModeling

Generally, 246112005 |Severity (attribute)| is not used to model concepts precoordinated in the International Release, but there are some exceptions. 

A valid exception requires an internationally accepted definition that can be consistently applied and used reliably for international comparison.  Even though a reference may be internationally sourced, its use may not always be uniformly applied by multiple countries. Classifications of severity that represent variation in clinical presentations and enact limitations with age ranges, sex, or pregnancy status, do not apply universally to all patients of all ages, prove problematic, and may not be generally useful. 

The requestor is responsible for obtaining permission for use in SNOMED CT if required by the international body.  

As an alternative to precoordination in the international release, this attribute can be used as a qualifier in postcoordination.  However, beware that postcoordination of severity results in the same irreproducibility issues as pre-coordination. 

Temporally related to

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726633004 |Temporally related to (attribute)| applies to perioperative complications

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and clinical findings where there is no causal relationship, but a time-relative association exists.

The attribute subhierarchy specifies the associated time period (i.e. before, during, after) between two procedures, two clinical findings, or a procedure and a clinical finding,

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e.g. perioperative complications

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temporally related to a surgical procedure (i.

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e. preoperative, intraoperative, and postoperative

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Concept
t726633004 |Temporally related to (attribute)|

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); Multisystem inflammatory syndrome in children temporally associated with SARS-CoV-2.  This attribute is self-grouped.