Medicinal Product Model

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changes.mady.by.user Julie M. James

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Example diagrams for MPF (containing)

Stated template view:Image Removed

Gliffy Diagram
size800
displayNameMedicinal Product Form
nameMedicinal Product Form
pagePin1

Figure 26: Medicinal Product Form (containing) stated template view

Example: single active ingredient product, oral dose form: stated view followed by the inferred view that shows the two proximal parent concepts associated with the product: 

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Example diagrams for MPF (only)

Stated template view:

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Gliffy Diagram
size800
displayNameMedicinal Product Form
nameMedicinal Product Form (only)
pagePin1

Figure 29: Medicinal Product Form (only) stated template view

Example: single active ingredient product, oral dose form: stated view followed by the inferred view that shows the proximal parent concepts associated with the product: 

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Semantic tag(medicinal product form)
Definition status


  • Scg expression
    900000000000073002 |Sufficiently defined concept definition status|


Exceptions

  • None identified
Role Group

Attribute

Scg expression
127489000 |Has active ingredient|


  • Range


    • Scg expression
      < 105590001|Substance|


      • Excluding concepts representing structural groupers, dispositions, or combined substances

    Cardinality

    • 1..* -

    Notes

    • There is no technical limit on the number of Has active ingredient attributes that may be added to a concept; a practical limit may be imposed at a later date
    • For content in the International Release, this attribute value should represent the base ingredient, not a modification, unless explicitly identified as an exception.
    • This attribute describes the set of active ingredient substances that the concept minimally contains. A set set of active ingredient substances may well have only one member

Attribute

Scg expression
411116001 |Has manufactured dose form|


Range


  • Scg expression
    < 736542009|Pharmaceutical dose form|


    • Only descendants that are groupers representing intended site only (e.g.
      Concept
      t385268001 |Oral dose form (dose form)|
      ,
      Concept
      t385287007 |Parenteral dose form (dose form)|
      )

Cardinality

  • 1..1

Notes

  • This attribute describes a grouping dose form concept for the medicinal product, where the grouping is the intended site for administration of the dose form of the product

Attribute

Scg expression
1142139005 |Count of base of active ingredient|


Range

  • INT (integer)

Cardinality

  • 1..1

Note

  • This attribute provides the number of base active ingredient substances present in the medicinal product

For concepts that have two or more active ingredient substances that are modifications of the same base substance, and where MP precisely concepts are required, and for single ingredient product concepts where the active substance is an ingredient in these multiple modification multi-ingredient products, the following extra ingredient count attribute will be required n order to support correct relationships generated by the MRCM:

Attribute 1142141006 |Count of base and modification pair|

Range

  • INT (integer)

Cardinality

  • 1..1

For concepts that have two or more active ingredient substances that are modifications of the same base active ingredient substance (i.e. parent ingredient substance) and where one is a further modification of the other (for example, a multi-ingredient product containing both dexamethasone phosphate and dexamethasone sodium phosphate, where the dexamethasone phosphate is a modification of dexamethasone (base) and dexamethasone sodium phosphate is a further modification of the dexamethasone phosphate) and where MP precisely concepts are required, and for single ingredient product concepts where the active substance is an ingredient in these multiple modification multi-ingredient products, the following extra ingredient count attribute will be required n order to support correct relationships generated by the MRCM:

Attribute 1142140007 |Count of active ingredient|

Range

  • INT (integer)

Cardinality

  • 1..1

As described in the MRCM rules, for practical and pragmatic reasons the additional ingredient count attributes have to be applied iteratively based on requirement. 

Use cases supported by MPF (only)

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