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  • 4.2 Terminology Bindings

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The FHIR AllergyIntolerence base resource is open to various choices of representation for the adverse sensitivity content per se, but often has restricted ways of providing qualifiers and modifiers.

Adverse sensitivity content value sets

The FHIR AllergyIntolerance base resource has example bindings to SNOMED CT for the element AllergyIntolerance.code as well as elements reaction.substance, reaction.manifestation, and reaction.exposureRoute. All example value sets are though very broad and likely not very precise in determining the set of relevant concepts, see table below. For each data element, the number of concepts that are in the Global Patient Set (GPS) is shown here. The GPS is a special SNOMED CT subset that can be used globally with minimal restriction and at no cost.

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Source

Name of value set

Steward

Number of concepts

Value Set Authority Center (VSAC), NLM[2]

Common dietary substances for allergy and intolerance documentation

HL7 Patient Care Workgroup

127

Value Set Authority Center (VSAC), NLM

Common drug classes for allergy and intolerance documentation

HL7 Patient Care Workgroup

42

Value Set Authority Center (VSAC), NLM

Common environmental substances for allergy and intolerance documentation

HL7 Patient Care Workgroup

15

Value Set Authority Center (VSAC), NLM

Common substances for allergy and intolerance documentation including refutations

HL7 Patient Care Workgroup

747 (also includes RxNorm entities)

Value Set Authority Center (VSAC), NLM

Food Allergen

Partners Healthcare

518

HL7

Allergy intolerance substance condition (GPS) – IPS[3]

FHIR GPS IG

784

HL7

Allergy Reaction (GPS) - IPS[4]

FHIR GPS IG

31

eHealth Digital Service Infrastructure (eHDSI)

IPS Allergy or Intolerance Conditions[5]

epSOS

15

eHealth Digital Service Infrastructure (eHDSI)

eHDSIAllergenNoDrug[6]

epSOS

158

eHealth Digital Service Infrastructure (eHDSI)

eHDSIAdverseEventType[7]

epSOS

10

 

Qualifier and/or modifier value sets

As a result of a request from HL7 to SNOMED International about the possibility of mapping some of the required HL7® FHIR® Value Sets to SNOMED CT, an analysis of the ability of SNOMED CT to accommodate those needs was performed by the SNOMED CT on FHIR Workgroup. The required value sets of the FHIR AllergyIntolerance resource was included in this analysis.

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In the analysis of the FHIR AllergyIntolerance required value sets, all but two were problematic in at least some way. The two straightforward mappable value sets were for elements AllergyIntolerance.reaction.severity and AllergyIntolerance.type

AllergyIntolerance.Reaction.Severity

It was assessed that there was a good match between the HL7 required value set and the SNOMED CT << 272141005 |Severities (qualifier value)| subhierarchy.

HL7 Code

HL7 Display

Suggested SNOMED CT concept

severe

Severe

24484000 |Severe (severity modifier) (qualifier value)|

moderate

Moderate

6736007 |Moderate (severity modifier) (qualifier value)|

mild

Mild

255604002 |Mild (qualifier value)|

AllergyIntolerance.Type

The group's suggested approach here is to use concepts taken from <<609433001 |Hypersensitivity disposition (finding)|unless an actual immune mediated hypersensitivity has been proven e.g., by testing. See section 6.1.1 Allergy list for a further discussion of the rationale behind this approach.

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