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Hi all,
We are looking for feedback related to this LOINC part and associated LOINC terms.
RELMA defines this property as following: “Risk is the probability (chance) of a certain event happening, such as developing a particular disease or inheriting a specific mutation. Risk can be represented as a fraction or a percent. For example, a 1 in 1,000 chance can be represented as 1/1,000 or 0.1%.”
Example LOINC terms that are using this property:
| LOINC_NUM | LONG_COMMON_NAME | COMPONENT | PROPERTY | TIME_ASPCT | SYSTEM | SCALE_TYP | METHOD_TYP |
| 43995-0 | Trisomy 21 risk [Likelihood] in Fetus | Trisomy 21 risk | Likelihood | Pt | ^Fetus | Qn |
|
| 49090-4 | Fetal Trisomy 21 risk [Likelihood] Based on maternal age | Trisomy 21 risk | Likelihood | Pt | ^Fetus | Qn | Based on maternal age |
| 73970-6 | Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free DNA by Dosage of chromosome-specific cfDNA | Trisomy 21 risk | Likelihood | Pt | Plas.cfDNA | Qn | Dosage of chromosome specific cf DNA |
| 75561-1 | Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | Trisomy 21 risk | Likelihood | Pt | WBC.DNA+Plas.cfDNA | Qn | Dosage of chromosome specific cf DNA |
| 75563-7 | Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | Trisomy 21 risk | Likelihood | Pt | WBC.DNA+Plas.cfDNA | Nar | Dosage of chromosome specific cf DNA |
For creating post coordinated expression for the examples noted above, our proposal is to:
Create new component concept as following:
7894007 | Karyotype morphology (morphologic abnormality)
78989007 | Trisomy (morphologic abnormality)
NEW | Trisomy 21 (morphologic abnormality)
Create a new property as following
New | Likelihood (property) (qualifier value)
Other attributes (including method) will be mapped as specified in the LOINC terms.
Best Regards,
Farzaneh
CC: Suzanne Santamaria