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  • 4.2 Terminology Bindings

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The FHIR AllergyIntolerance base resource has example bindings to SNOMED CT for the element AllergyIntolerance.code as well as elements reaction.substance, reaction.manifestation, and reaction.exposureRoute. All example value sets are though very broad and likely not very precise in determining the set of relevant concepts, see table below. For each data element, the number of concepts that are in the Global Patient Set (GPS) is shown here. The GPS is a special SNOMED CT subset that can be used globally with minimal restriction and at no cost.

 

FHIR element

SNOMED CT value set

Corresponding ECL

# concepts (in GPS version 2020-7-31)

AllergyIntolerance.code

https://www.hl7.org/fhir/valueset-allergyintolerance-code.html

If recording is based on substances and products and specifies the type of reaction in "type":

<<105590001 | Substance (substance) | OR <<373873005 | Pharmaceutical / biologic product (product) |

OR

If recording is based on finding concepts precoordinating the type of reaction :

<<418038007 |Propensity to adverse reactions to substance|

OR

When using precoordianted Situation concepts to represent the absence of an allergic propensity

<<716186003 |No known allergy|[1]

51133 (1157)

AllergyIntolerance. reaction.substance

https://www.hl7.org/fhir/valueset-substance-code.html

<<105590001 | Substance (substance) | OR <<373873005 | Pharmaceutical / biologic product (product) |

49763  (1132)

AllergyIntolerance. reaction.manifestation

https://www.hl7.org/fhir/valueset-clinical-findings.html

<<404684003 |Clinical finding|

114493  (12135)

AllergyIntolerance. reaction.exposureRoute

https://www.hl7.org/fhir/valueset-route-codes.html

<<284009009 |Route of administration value|

163 (20)

Since the SNOMED CT value sets in this category usually include a large number of concepts, implementers often ask for lists of most frequently used concepts to facilitate implementation (e.g., building picklists to assist data entry). These frequently-used subsets are sometimes called “starter sets”. Examples of starter sets are:

 

Source

Name of value set

Steward

Number of concepts

Value Set Authority Center (VSAC), NLM[2]

Common dietary substances for allergy and intolerance documentation

HL7 Patient Care Workgroup

127

Value Set Authority Center (VSAC), NLM

Common drug classes for allergy and intolerance documentation

HL7 Patient Care Workgroup

42

Value Set Authority Center (VSAC), NLM

Common environmental substances for allergy and intolerance documentation

HL7 Patient Care Workgroup

15

Value Set Authority Center (VSAC), NLM

Common substances for allergy and intolerance documentation including refutations

HL7 Patient Care Workgroup

747 (also includes RxNorm entities)

Value Set Authority Center (VSAC), NLM

Food Allergen

Partners Healthcare

518

HL7

Allergy intolerance substance condition (GPS) – IPS[3]

FHIR GPS IG

784

HL7

Allergy Reaction (GPS) - IPS[4]

FHIR GPS IG

31

eHealth Digital Service Infrastructure (eHDSI)

IPS Allergy or Intolerance Conditions[5]

epSOS

15

eHealth Digital Service Infrastructure (eHDSI)

eHDSIAllergenNoDrug[6]

epSOS

158

eHealth Digital Service Infrastructure (eHDSI)

eHDSIAdverseEventType[7]

epSOS

10

 

Qualifier and/or modifier value sets

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It was assessed that there was a good match between the HL7 required value set and the SNOMED CT << 272141005 |Severities (qualifier value)| subhierarchy.

HL7 Code

HL7 Display

Suggested SNOMED CT concept

severe

Severe

24484000 |Severe (severity modifier) (qualifier value)|

moderate

Moderate

6736007 |Moderate (severity modifier) (qualifier value)|

mild

Mild

255604002 |Mild (qualifier value)|

AllergyIntolerance.Type

The group's suggested approach here is to use concepts taken from <<609433001 |Hypersensitivity disposition (finding)|unless an actual immune mediated hypersensitivity has been proven e.g., by testing. See section 6.1.1 Allergy list for a further discussion of the rationale behind this approach.

HL7 Code

HL7 Display

Suggested SNOMED CT concept

allergy

Allergy

609433001 |Hypersensitivity disposition (finding)|

intolerance

Intolerance

782197009 |Intolerance to substance (finding)|

For other required value sets in the FHIR AllergyIntolerance resource there were issues ranging from some concepts in the FHIR value set lacked a corresponding SNOMED CT concept to differences in the underlying ontology making mapping complicated and likely less useful. For more details about mapping FHIR value sets to SNOMED CT, refer to the discussion of the SNOMED on FHIR Workgroup.[8]

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