Observable entity concepts representing histopathology examination observables of neoplasms are being modeled according to a series of templates.
Please see the templates listed here: https://confluence.ihtsdotools.org/x/SonUAw. See the Community Content area for more information about the project.
Concepts containing a primary malignant neoplasm from the observable entity subhierarchy employ the 704321009 |Characterizes (attribute)| with the target qualifier value of 1234914003 |Malignant proliferation of primary neoplasm (qualifier value)| in order to define primary (which matches the target value of the Pathological process (attribute) used by concepts in the Disorder hierarchy).
For example,
1136681000004107 |Anatomic location of excised primary malignant neoplasm (observable entity)| applies the Characterizes (attribute) with a target of Malignant proliferation of primary neoplasm (qualifier value).
Figure 1: Stated view of 1136681000004107 |Anatomic location of excised primary malignant neoplasm (observable entity)|
Figure 2: Stated view of 372087000 |Primary malignant neoplasm (disorder)|
Concepts containing a metastatic malignant neoplasm from the observable entity subhierarchy do not use 704321009 |Characterizes (attribute)|, but instead are defined by the specific metastatic morphologic abnormality. For example, 444384007 |Number of regional lymph nodes containing metastatic neoplasm in excised specimen (observable entity)| has the attribute 246093002 |Component (attribute)| with a target value of 14799000 |Neoplasm, metastatic (morphologic abnormality)|.
Colorectum
The terms colorectal and colorectum, commonly used by pathologists, are included in descriptions for concepts referring to neoplasms modeled with 1285733009 |Structure of cecum and/or colon and/or rectum (body structure)|. 1285733009 |Structure of cecum and/or colon and/or rectum (body structure)| is needed because neoplasms are the same from the cecum to rectum and are considered as a group in cancer synoptic reporting protocols. Note, there is no consensus concerning the definition of colon in the literature and between different domains.
Concepts containing a metastatic malignant neoplasm from the observable entity subhierarchy do not use 704321009 |Characterizes (attribute)|, but instead are defined by the specific metastatic morphologic abnormality. For example, 444384007 |Number of regional lymph nodes containing metastatic neoplasm in excised specimen (observable entity)| has the attribute 246093002 |Component (attribute)| with a target value of 14799000 |Neoplasm, metastatic (morphologic abnormality)|.
Concepts containing a metastatic malignant neoplasm from the observable entity subhierarchy do not use 704321009 |Characterizes (attribute)|, but instead are defined by the specific metastatic morphologic abnormality. For example, 444384007 |Number of regional lymph nodes containing metastatic neoplasm in excised specimen (observable entity)| has the attribute 246093002 |Component (attribute)| with a target value of 14799000 |Neoplasm, metastatic (morphologic abnormality)|.
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